Hubungan Jumlah Monosit Dan Nilai Laju Endap Darah (LED) Terhadap Lama Pengobatan Pasien Tuberculosis

Correlation Of Monocyte Number And Erythrocyte Sedimentation Rate (Esr) Value Against To Duration Of Treatment In Tuberculosis Patients

Authors

  • Ari Kadarwati Universitas Muhammadiyah Semarang
  • Andri Sukeksi Universitas Muhammadiyah Semarang
  • Gela Setya Ayu Putri Universitas Muhammadiyah Semarang

DOI:

https://doi.org/10.33084/bjmlt.v6i1.6077

Keywords:

Tuberculosis, Monocytes, Sedimentation Rate, Duration of Treatment Tuberculosis

Abstract

Tuberculosis (TBC) is a bacterial infection caused by Mycobacterium tuberculosis. The duration of TBC treatment is routinely 6 months; otherwise, resistance will develop. TBC can increase leukocytes, including monocytosis as an inflammatory response and an elevated ESR.  The aim of this study was to determine the relationship between the number of monocytes and the ESR value on the duration of tuberculosis treatment in patients at the Respira Lung Hospital, Yogyakarta City. The study was conducted in June and July 2023 at the Respira Pulmonary Hospital in Yogyakarta City. The study sample was 32 tuberculosis patients and blood was drawn to determine the monocyte number and ESR value. The results showed that the average number of monocytes was 7% (normal), the ESR value was 41.59 mm/hour (high) with the average duration of tuberculosis treatment for respondents was 3 months. Spearman test obtained Sig p<0.05.  This study concluded that there is a correlation between the number of monocytes and the ESR value on the duration of TB treatment in patients at the Respira Lung Hospital in Yogyakarta City, with the direction of the relationship reversed.

Downloads

Download data is not yet available.

References

Bain, B. 2015. Penuntun Praktikum Hematologi. Makassar: Fakultas Kedokteran UNHAS.

Bochen K, Krasowska A, Milaniuk S. 2011. Erhytrocyte Sedimentation Rate - an Old Marker With New Application. Journal of Pre-Clinical Research.

Brajadenta, GS., Sumaerah, DS. 2019. Efek terapi Obat Anti Tuberculosis terhadap Laju Endap Darah. Jurnal Ilmiah Ilmu Kesehatan: Wawasan Kesehatan 5 (2), 111-116, 2019.

Budiartani, Y. 2020. Gambaran asuhan keperawatan pada pasien Tuberculosis paru dalam pemenuhan defisit pengetahuan di wilayah kerja UPT Puskesmas 1 Abiansemal Tahun 2020. Jurnal Poltekkes Denpasar. Diakses 29 juli 2023.

Chairani M, 2019. Membandingkan Jumlah Leukosit dan Nilai Laju Endap Darah pada Pasien Tuberculosis Paru Sebelum dan Setelah Pengobatan. Jurnal Sains dan Teknologi 10 (1), 10-12, 2019.

Darliana, D. 2011. Manajemen Pasien Tuberculosis Paru. Jurnal PSIK–FK Unsyiah . ISSN :2087-2879. Diakses pada tanggal 11 Oktober 2018.

Dekayana A, 2019. Hitung Laju Endap Darah (LED). Uwais Inspirasi Indonesia, Ponorogo.

Departemen Kesehatan RI. 2014. Pedoman Nasional Penanggulangan Tuberkulosis. Jakarta: DepKes RI.

Dinas Kesehatan Kota Yogyakarta. 2022. Profil Kesehatan Kota Yogyakarta. Yogyakarta : Dinkes Kota Yogyakarta.

Estridge B, Reynold A. 2012. Basic Clinical Laboratory Techniques Sixth Edition. USA : Delmar Cengage Learning.

Feldman M, Aziz Bilal. 2013. C-Reactive Protein and Erhytrocyte Sedimentation Rate Discordance : Frecuency and Causes in Adults Translational Research Elsevier.

Ibrahim N, Aprianti S, Arif M, Hardjoeno H. 2016. Hasil Tes Laju Endap Darah Cara Manual dan Automatic. Indonesia Journal : Clinical Pathology and Medical Laboratory.

Isbaniah, F., Burhan, E., Sinaga, Y. B., Bethri, D., Yanifitri, Handayani Diah, Harsini, Agustin, H. H., Artika, N. I., Aphridasari, J., Lasmaria Rohani, Russilawati, Soedarsono, Sugiri, Y. J. R. 2021. Pedoman Diagnosis Dan Penatalaksanaan Tuberculosis Di Indonesia. 2021.

Ismail A, Handayany GN, Bakri M. 2016. Evaluasi Penggunaan Obat Anti Tuberculosis (OAT) Pada Pasien Tuberculosis Paru di Puskesmas Jumpadang Baru Makassar,. Jurnal Farmasi UIN Alauddin Makassar, 4(4), 194-206.

Isselbacher, Braunwald, Wilson, Martin, Fauci, Kasper. 2012. Prinsip-prinsip Ilmu Penyakit Dalam. Alih bahasa Asdie, A. Edisi 13. Jakarta : EGC.

Kemenkes RI, 2012. Pedoman Pencegahan dan Pengendalian Tuberculosis di Fasilitas Kesehatan.

Kemenkes RI. 2016. Peraturan Menteri Kesehatan Republik Indonesia Nomor 67 Tahun 2016 Tentang penanggulangan Tuberculosis.

Kementrian Kesehatan RI. 2018. Pedoman Nasional Pengendalian Tuberculosis. Direktorat Jendral Pengendalian Penyakit dan Penyehatan Lingkungan Kementrian Kesehatan RI.

Kementrian Kesehatan. 2022. Pertemuan Nasional Monitoring dan Evaluasi Program Tuberkulosis Tahun 2022. Jakarta : Dirjen P2P

Kumta S. 2011. A Comparative Study Of Erythrochyte Sedimentation Rate (Esr) Using Sodium Citrate And EDTA. International Journal Of Pharmacy And Biological Sciences 1(4).

Lestari, W. 2017. Profil Laju Endap Darah Pasien Tuberkulosis Paru Kasus Baru di RSU Kota Tanggerang Selatan. Jakarta : Universitas Islam Negeri Syarif Hidayatullah.

Notoadmodjo, S. 2012. Metodologi Penelitian Kesehatan. Jakarta: Rineke Cipta.

Nugraha, G. 2015. Panduan Pemeriksaan Laboratorium Hematologi Dasar. Jakarta Timur: CV. Trans Info Media.

Sari, WD. 2021. Upaya pengendalian Tuberculosis dengan meningkatkan kepatuhan minum obat anti Tuberculosis. Media Kesehatan Indonesia, Vol 2, no 3,pp.200-205, Juni 2021. Ejournal.undip.ac.id.

Sudoyo AW, Alwi I, Sumadibrata M, Setiadi S. 2009. Buku Ajar Ilmu Penyakit Dalam Jilid II edisi V. Jakarta : Interna Publishing.

Syahrezki, M. 2015. Faktor Resiko Tuberculosis Multidrug Resistant (TBMDR). Jurnal Agromed Unila.2(4):413-418

Tahumuri A, Wongkar L, Rotty . 2017. Gambaran Laju Endap Darah Dan C-Reactive Protein Pada Pasien Tuberkulosis Paru Di Manado 2016. Jurnal Kedokteran Klinik (JKK) 1(3).

Wahid A, Suprapto. 2013. Keperawatan Medikal Bedah (Asuhan Keperawatan pada Gangguan Sistem Respirasi. Jakarta : CV Trans Info Media.

World Health Organization (WHO). 2020. Global Tuberculosis Report 2020. Geneva: WHO Press.

Downloads

Published

2023-10-31

How to Cite

Kadarwati, A., Sukeksi, A., & Putri, G. S. A. (2023). Hubungan Jumlah Monosit Dan Nilai Laju Endap Darah (LED) Terhadap Lama Pengobatan Pasien Tuberculosis : Correlation Of Monocyte Number And Erythrocyte Sedimentation Rate (Esr) Value Against To Duration Of Treatment In Tuberculosis Patients. Borneo Journal of Medical Laboratory Technology, 6(1), 394–399. https://doi.org/10.33084/bjmlt.v6i1.6077