Research Trends in Ethnomedicine-Based Anti-Diabetic Medicinal Plants: A Bibliometric Analysis (2010–2025)
Main Article Content
Abstract
Studi ini bertujuan untuk mengindentifikasi dan memulai penelitian tentang tanaman obat anti-diabetes berbasis etnomedis. Studi ini selain menggunakan analisis bibliometrik, juga memanfaatkan perangkat lunak VOSviewers untuk memvisualisasikan jaringan, tren, dan karakteristik penelitian tentang tanaman obat dalam 15 tahun terakhir berbasis database Scopus. Dari penemuan 116 jumlah total dokumen publikasi penelitian tanaman obat dalam 15 tahun terakhir, negara India, Nigeria, Bangladesh, menjadi negara paling aktif dalam penerbitan penelitian tanaman obat dalam 15 tahun terakhir. Universitas University of Nigeria, University of Development Alternative, dan University of Ibadan menjadi afiliasi terbanyak dalam mempublikasikan penelitian tanaman obat. Mohammed Salim Rahmatullah dari Bangladesh, Rainer W. Bussmann dari Georgia, dan Rownak Jahan dari Bangladesh menjadi penulis paling konsisten mempublikasikan penelitian tanaman obat dalam 15 tahun terakhir. Studi ini juga merekomendasikan pentingnya studi-studi di masa yang akan datang untuk membahas potensi kandungan senyawa dalam tanaman obat, khususnya dalam konteks penanganan penyakit kronis seperti diabetes.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
All rights reserved. This publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording.
References
Akther, Y., Nabi, J., & Tabassum, N. (2022). Comprehensive Overview of Some Edible Medicinal Plants from Kashmir Valley: Cultural, Economic, and Pharmacological Importance. In Edible Plants in Health and Diseases (pp. 137–159). Springer Nature Singapore. https://doi.org/10.1007/978-981-16-4880-9_6
Al Jaafreh, A. M. (2024). Investigation of the phytochemical profiling and antioxidant, anti-diabetic, anti-inflammatory, and MDA-MB-231 cell line antiproliferative potentials of extracts from Ephedra alata Decne. Scientific Reports, 14(1), 18240. https://doi.org/10.1038/s41598-024-65561-9
Azizah, A. N., & Kurniati, C. H. (2020). Obat herbal tradisional pereda batuk pilek pada balita. Jurnal Kebidanan Indonesia, 11(2), 29–36. https://jurnal.stikesmus.ac.id/index.php/JKebIn/article/view/370
Azmin, N. N., & Anita rahmawati, A. rahmawati. (2019). Inventarisasi Tumbuhan Obat Tradisional Di Kecamatan Wera Kabupaten Bima. ORYZA (Jurnal Pendidikan Biologi), 8(2), 34–39. https://doi.org/10.33627/oz.v8i2.293
Birru, E. M., Abdelwuhab, M., & Shewamene, Z. (2015). Effect of hydroalcoholic leaves extract of Indigofera spicata Forssk. on blood glucose level of normal, glucose loaded and diabetic rodents. BMC Complementary and Alternative Medicine, 15(1), 321. https://doi.org/10.1186/s12906-015-0852-8
Borkatulla, B., Ferdous, J., Uddin, A. H., & Mahmud, P. (2023). Bangladeshi medicinal plant dataset. Data in Brief, 48, 109211. https://doi.org/10.1016/j.dib.2023.109211
Chen, D. Q., Wu, J., & Li, P. (2022). Therapeutic mechanism and clinical application of Chinese herbal medicine against diabetic kidney disease. In Frontiers in Pharmacology (Vol. 13). https://doi.org/10.3389/fphar.2022.1055296
Chihomvu, P., Ganesan, A., Gibbons, S., Woollard, K., & Hayes, M. A. (2024). Phytochemicals in Drug Discovery—A Confluence of Tradition and Innovation. International Journal of Molecular Sciences, 25(16), 8792. https://doi.org/10.3390/ijms25168792
Dewi, T., Yustika, R. D., & Arianti, F. D. (2024). Enhancement of Production and Food Security Through Sustainable Shallot Cultivation. IOP Conference Series: Earth and Environmental Science, 1364(1), 012052. https://doi.org/10.1088/1755-1315/1364/1/012052
Dharmastuti, W., Elya, B., Hanafi, M., & Lotulung, P. D. N. (2024). Phytochemical Constituents, Anti-Diabetic and Antioxidant Activities of Methanol Extracts of Diospyros malabarica (Desr.) Kostel Leaves and Stem Bark. Tropical Journal of Natural Product Research, 8(5), 7249–7258. https://doi.org/10.26538/tjnpr/v8i5.29
Dilip Bhandare, S. (2025). Exploration of medicinal plants as potential therapeutics against COVID-19: molecular insights and drug development prospects with other significant medicinal information a retrospective exposition. Journal of Pharmacy and Pharmacology, 77(1), 18–31. https://doi.org/10.1093/jpp/rgae074
Fahmi, S., Winarno, B., Nugraha, L. M., Lestari, S., & Yuwati, T. W. (2023). Food plant biodiversity and conservation of upland landscape in Indonesia for sustainable development: A review. 9th International Symposium on Innovative Bioproduction Indonesia on Biotechnology and Bioengineering 2022: Strengthening Bioeconomy through Applied Biotechnology, Bioengineering, and Biodiversity, ISIBio 2022, 070012. https://doi.org/10.1063/5.0183714
Faujdar, C., & Priyadarshini. (2019). Natural Compounds Extracted from Medicinal Plants and Their Applications in Cardiovascular and Kidney Diseases. In Natural Bio-active Compounds (pp. 297–312). Springer Singapore. https://doi.org/10.1007/978-981-13-7205-6_13
Fernando, H., Larasati, Y. G., Abdullah, I., Firdawaty, L., & Qodriyah, K. (2024). Bibliometrics of Family Law Research Trends in Southeast Asia: An Analysis Two Decades 2003-2023. El-Usrah: Jurnal Hukum Keluarga, 7(1), 82–109. https://jurnal.ar-raniry.ac.id/index.php/usrah/index
Ghosh, D., Adhikary, S., Bhattacherjee, P., & Debnath, S. (2024). Herbal Medicine for Health Management and Disease Prevention. In Herbal Medicine Phytochemistry (pp. 1–35). https://doi.org/10.1007/978-3-031-21973-3_31-1
Governa, P., Baini, G., Borgonetti, V., Cettolin, G., Giachetti, D., Magnano, A., Miraldi, E., & Biagi, M. (2018). Phytotherapy in the Management of Diabetes: A Review. Molecules, 23(1), 105. https://doi.org/10.3390/molecules23010105
Guan, Y., Tang, G., Li, L., Shu, J., Zhao, Y., Huang, L., & Tang, J. (2024). Herbal medicine and gut microbiota: exploring untapped therapeutic potential in neurodegenerative disease management. In Archives of Pharmacal Research. https://doi.org/10.1007/s12272-023-01484-9
Hertiani, T., Endra Pujiastuti, Agung Endro Nugroho, & Khoirun Nisa. (2023). Revealing the contribution of phytochemicals in Syzygium cumini as-diabetics: A Systematic Review. In Indonesian Journal of Pharmacy. https://doi.org/10.22146/ijp.6812
Huang, X., Gull, N., Hussain, L., Bazmi, R. R., Jamshed, A., Siddique, R., Riaz, M., & Rahman, H. M. A. (2024). The Emerging Trend of Phytochemicals and Nutraceuticals-Based Traditional Medicines and Their Role in Chronic Disease Management. Journal of Biological Regulators and Homeostatic Agents, 38(1), 31–45. https://doi.org/10.23812/j.biol.regul.homeost.agents.20243801.3
Ismail, M., & Imam, M. U. (2014). Plant Bioresources and their Nutrigenomic Implications on Health. In Novel Plant Bioresources (pp. 383–394). Wiley. https://doi.org/10.1002/9781118460566.ch27
Kamyab, R., Namdar, H., Torbati, M., Ghojazadeh, M., Araj-Khodaei, M., & Fazljou, S. M. B. (2020). Medicinal Plants in the Treatment of Hypertension: A Review. Advanced Pharmaceutical Bulletin, 11(4), 601–617. https://doi.org/10.34172/apb.2021.090
Larasati, Y. G., Fernando, H., Abdullah, I., Harpawati, T., & Morin, L. (2025). Bibliometric Analysis of 20 years of Traditional Music Research in Asia. Resital: Jurnal Seni Pertunjukan, 25(3), 392–413. https://doi.org/10.24821/resital.v25i3.14983
Leonida, A. M. G., & Caballero, A. R. (2022). Aleaf: An Android-Based Phytotherapy Leaf Recognition Using Custom Vision Machine Learning. 2022 7th International Conference on Business and Industrial Research (ICBIR), 488–493. https://doi.org/10.1109/ICBIR54589.2022.9786509
Marwati, M., & Amidi, A. (2019). Pengaruh budaya, persepsi, dan kepercayaan terhadap keputusan pembelian obat herbal. Jurnal Ilmu Manajemen, 7(2), 168–180. https://jurnal.um-palembang.ac.id/ilmu_manajemen/article/view/1567
Montasir, L. O., Salzabil, A. Z. A., Rafiun, N. A. S., Kasih, M., & Marsaban, A. (2023). The utilization of medicinal plants in Kolaka local community: An ethnobotanical study. IAS Journal of Localities, 1(2), 81–92. https://doi.org/10.62033/iasjol.v1i2.19
Navia, Z. I., Audira, D., Afifah, N., Turnip, K., NURAINI, N., & Suwardi, A. B. (2020). Ethnobotanical investigation of spice and condiment plants used by the Taming tribe in Aceh, Indonesia. Biodiversitas Journal of Biological Diversity, 21(10), 4467–4473. https://doi.org/10.13057/biodiv/d211001
Ngandjui, Y. A. T., Tchamgoue, J., Kagho, D. U. K., Msagati, T. A. M., Ngameni, B., & Kouam, S. F. (2023). Chemical Characterization of Phytoconstituents for Lifestyle Diseases. In Role of Herbal Medicines (pp. 59–87). Springer Nature Singapore. https://doi.org/10.1007/978-981-99-7703-1_4
Nworu, C. S., Udeogaranya, P. O., Okafor, C. K., Adikwu, A. O., & Akah, P. A. (2015). Perception, usage and knowledge of herbal medicines by students and academic staff of University of Nigeria: A survey. European Journal of Integrative Medicine, 7(3), 218–227. https://doi.org/10.1016/j.eujim.2015.01.005
Pane, M., Rahman, A., & Ayudia, E. (2021). Gambaran penggunaan obat herbal pada masyarakat indonesia dan interaksinya terhadap obat konvensional tahun 2020. Journal of Medical Studies, 1(1), 40–62. https://online-journal.unja.ac.id/joms/article/view/14527
Pillay, M., Takaidza, S., Madike, L. N., & Terblanche, U. (2022). Conservation of Medicinal Plant Genetic Resources in Southern Africa. In Plant Genetic Resources, Inventory, Collection and Conservation (pp. 319–338). Springer Nature Singapore. https://doi.org/10.1007/978-981-16-7699-4_15
Pirintsos, S., Panagiotopoulos, A., Bariotakis, M., Daskalakis, V., Lionis, C., Sourvinos, G., Karakasiliotis, I., Kampa, M., & Castanas, E. (2022). From Traditional Ethnopharmacology to Modern Natural Drug Discovery: A Methodology Discussion and Specific Examples. Molecules, 27(13), 4060. https://doi.org/10.3390/molecules27134060
Prabakaran, S., Saad, H. M., Tan, C. H., Syed Abdul Rahman, S. N., & Sim, K. S. (2025). Investigation of Phytochemical Composition, Radical Scavenging Potential, Anti‐Obesogenic Effects, and Anti‐Diabetic Activities of Kaempferia parviflora Rhizomes. Chemistry & Biodiversity, 22(1). https://doi.org/10.1002/cbdv.202401086
Prasathkumar, M., Anisha, S., Dhrisya, C., Becky, R., & Sadhasivam, S. (2021). Therapeutic and pharmacological efficacy of selective Indian medicinal plants – A review. Phytomedicine Plus, 1(2), 100029. https://doi.org/10.1016/j.phyplu.2021.100029
Pujiasmanto, B., & Rumia Manurung, I. (2022). Identification of Sambiloto agroecology as a basis for utilization and conservation of germplasm. IOP Conference Series: Earth and Environmental Science, 1016(1), 012004. https://doi.org/10.1088/1755-1315/1016/1/012004
R.K., K., M.N., N., A.H., Z., & Astuti, P. D. (2023). Total phenolic content and anti-diabetic activity of dried and fresh leaves of Ocimum sanctum (Linn). Food Research, 7(Supplementary 4), 139–145. https://doi.org/10.26656/fr.2017.7(S4).18
Rahmat, E., Lee, J., & Kang, Y. (2021). Javanese Turmeric (Curcuma xanthorrhiza Roxb.): Ethnobotany, Phytochemistry, Biotechnology, and Pharmacological Activities. Evidence-Based Complementary and Alternative Medicine, 2021, 1–15. https://doi.org/10.1155/2021/9960813
Rambey, R., Tambunan, W. A., Hasibuan, M., Siregar, F. A., Prayogo, B., Silalahi, C., Hasibuan, D., & Syahputra, N. (2021). Ethnobotany of the Arecaceae family in Torgamba District, South Labuhanbatu, North Sumatra. IOP Conference Series: Earth and Environmental Science, 782(3), 032022. https://doi.org/10.1088/1755-1315/782/3/032022
Rosa, D., Elya, B., Hanafi, M., Khatib, A., & Surya, M. I. (2022). In Vitro and In Silico Screening Analysis of Artabotrys sumatranus Leaf and Twig Extracts for α-Glucosidase Inhibition Activity and Its Relationship with Antioxidant Activity. Scientia Pharmaceutica, 91(1), 2. https://doi.org/10.3390/scipharm91010002
Sabbagh, B. A., Palanirajan, V. K., Chew, Y.-L., Chin, J. H., Ahmad, M., & Akowuah, G. A. (2025). UHPLC-MS/MS standardized extract of Vernonia amygdalina leaf inhibits CYP2C9 and CYP3A4 activities in hepatic cells of control and streptozotocin-induced diabetic rats. Drug Metabolism and Personalized Therapy, 39(4), 231–241. https://doi.org/10.1515/dmpt-2024-0005
Sharma, A. N., Dewangan, H. K., & Upadhyay, P. K. (2024). Comprehensive Review on Herbal Medicine: Emphasis on Current Therapy and Role of Phytoconstituents for Cancer Treatment. Chemistry & Biodiversity, 21(3), e202301468. https://doi.org/10.1002/cbdv.202301468
Singh, M., Ali, A. A., & Irfan Qureshi, M. (2017). Unravelling the Impact of Essential Mineral Nutrients on Active Constituents of Selected Medicinal and Aromatic Plants. In Essential Plant Nutrients (pp. 183–209). Springer International Publishing. https://doi.org/10.1007/978-3-319-58841-4_9
Soto, K. M., Pérez Bueno, J. de J., Mendoza López, M. L., Apátiga-Castro, M., López-Romero, J. M., Mendoza, S., & Manzano-Ramírez, A. (2023). Antioxidants in Traditional Mexican Medicine and Their Applications as Antitumor Treatments. Pharmaceuticals, 16(4), 482. https://doi.org/10.3390/ph16040482
Thakur, M., Verma, R., Kumar, D., Manickam, S., Ullah, R., Ibrahim, M. A., Bari, A., Lalhenmawia, H., & Kumar, D. (2024). Hypoglycemic and antioxidant activities of Jasminum officinale L. with identification and characterization of phytocompounds. Heliyon, 10(21), e39165. https://doi.org/10.1016/j.heliyon.2024.e39165
Utami, N. R., Rahayuningsih, M., Abdullah, M., & Ahmad, T. A. (2019). Preliminary study of ethnobotany based on local wisdom in Mount Ungaran Central Java. Journal of Physics: Conference Series, 1321(3), 032034. https://doi.org/10.1088/1742-6596/1321/3/032034
Vadivu, R. S., Bakthavatchalam, S., Rani, V. G., Hirad, A. H., Wen, Z.-H., Yuan, C.-H., & Vinayagam, R. (2024). Assessment of anti-diabetic properties of Ziziphus oenopolia (L.) wild edible fruit extract: In vitro and in silico investigations through molecular docking analysis. Open Chemistry, 22(1), 20240032. https://doi.org/10.1515/chem-2024-0032
Wardhani, R. P., Ningsih, R. R., Ramadhona, R., Astuti, H. P., & Fitriyani, N. (2013). Teh Biji Semangka (Citrullus lanatus) Sebagai Obat Herbal Alternatif Jantung Dan Anti Kanker. Jurnal Kesehatan Kusuma Husada, 4(2), 84–88. https://jurnal.ukh.ac.id/index.php/JK/article/view/65
Widodo. (2015). Bioinformatics: Cheap and robust method to explore biomaterial from Indonesia biodiversity. Irago Conference 2014: A 360 Degree Outlook at Critical Scientific and Technological Challenges for a Sustainable Society, 148–151. https://doi.org/10.1063/1.4913560
Zeng, W., Li, H., Liu, S., Luo, Z., Chen, J., & Zhou, J. (2025). Biosynthesis and bioactivities of triterpenoids from Centella asiatica: Challenges and opportunities. Biotechnology Advances, 80, 108541. https://doi.org/10.1016/j.biotechadv.2025.108541
Zubaidi, S. N., Mohd Nani, H., Ahmad Kamal, M. S., Abdul Qayyum, T., Maarof, S., Afzan, A., Mohmad Misnan, N., Hamezah, H. S., Baharum, S. N., & Mediani, A. (2023). Annona muricata: Comprehensive Review on the Ethnomedicinal, Phytochemistry, and Pharmacological Aspects Focusing on Antidiabetic Properties. Life, 13(2), 353. https://doi.org/10.3390/life13020353