In-Vitro Study of Antioxidant Activities from Ethanol Extracts of Akar Kuning (Arcangelisia flava)
DOI:
https://doi.org/10.33084/jsm.v4i2.594Keywords:
Arcangelisia flava, antioxidant, DPPHAbstract
This study aims to determine the antioxidant activity of akar kuning (Arcangelisia flava) stem extract from Central Kalimantan using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. This research includes extraction of simplicia and test of antioxidant activity by DPPH method. Based on the analysis of antioxidant activity on ethanol extract from yellow root plant stem IC50 values of 136.81 ppm were obtained. This IC50 value indicates the antioxidant strength of the yellow root plant stems including in the moderate category. Further research on antioxidant activity in the fraction of akar kuning stems needs to be done to determine the composition of the antioxidant compounds in each solvent.
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References
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Badarinath, A.V., Rao, K.M, Chetty, C.M.S., Ramkanth, S., Rajan, T.V.S., & Gnanaprakash, K. 2010. A Review on In-vitro Antioxidant Methods: Comparisions, Correlations and Considerations. International Journal of PharmTech Research, 2(2): 1276-1285.
Dezsi, S., Badarau, A.S., Bischin, C., Vodnar, D.C., Silaghi-Dumitrecu, R., Gheldiu, A.M., Mocan, A., & Vlase, L. 2015. Antimicrobial and antioxidant activities and phenolic profile of Eucalyptus globulus Labill. and Corymbia ficifolia (F.Muell.) K.D.Hill & L.A.S. Johnson Leaves. Molecules. Vol. 20 No.3 : 4720 – 4734.
Irnawati, I., Purba, M., Mujadilah, R., & Sarmayani, S. 2017. Penetapan Kadar Vitamin C dan Uji Aktifitas Antioksidan Sari Buah Songi (Dillenia serrata Thunb.) terhadap Radikal DPPH (Diphenylpicrylhydrazyl). Pharmacon, Vol. 6 No. 2 : 40-44.
Jayaprakasha, G.K., Singh, R.P., & Sakariah, K.K. 2001. Antioxidant activity of grape seed (Vitis vinifera) ectracts on peroxidation models in vitro. Food Chemistry. Vol. 73 : 285 – 290.
Jayaprakasha GK, Selvi T, & Sakariah KK. 2003. Antibacterial and antioxidant activities of grape (Vitis vinifera) seed extracts. Food Research International. Vol. 36 :117-122.
Kasote, D.M., Katyare, S.S., Hedge, M.V., Bae, H. Significance of antioxidant potential of plants and its relevance to therapeutic applications. International Journal of Biological Sciences. Vol. 11 No. 8 : 982 – 991.
Kedare, S.B. & Singh, R.P. 2011. Genesis and development of DPPH method of antioxidant assay, Journal of Food Science and Technology, Vol. 48 No. 4 : 412-422.
Molyneux, P. 2004. The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity. Songklanakarin Journal of Science and Technology, 26(2) : 211-219.
Muharni, M., Elfita, E., & Amanda, A. 2013. Aktivitas Antioksidan Senyawa (+) Morelloflavon dari Kulit Batang Tumbuhan Gamboge (Garcinia xanthochymus). Prosiding Semirata FMIPA Universitas Lampung, Lampung. 265-268.
Pratama, M.R.F. 2016. Akar kuning (Arcangelisia flava) sebagai inhibitor EGFR: Kajian in silico. Jurnal Pharmagazine. Vol. 3 No. 1 : 6 – 16.
Pratama, M.R.F. 2017. Akar kuning (Arcangelisia flava) as neuraminidase inhibitor: Molecular docking and pharmacophore optimization approach. Advances in Health Science Research. Vol. 6 : 502 – 511.
Pratama, M.R.F., Suratno, & Mulyani, E. 2018. Antibacterial Activity of Akar Kuning (Arcangelisia flava) Secondary Metabolites: Molecular Docking Approach. Asian Journal of Pharmaceutical and Clinical Research. Vol. 11 No. 11 : 447-451.
Rohyani, I.S., Aryanti, E., Suripto. Kandungan fitokimia beberapa jenis tumbuhan lokal yang sering dimanfaatkan sebagai bahan baku obat di Pulau Lombok. Prosiding Seminar Nasional Masyarakat Biodiversitas Indonesia. Vol. 1 No. 2 : 388 – 391.
Setyowati, Francisca Murti. 2010. Etnofarmakologi dan Pemakaian Tanaman Obat Suku Dayak Tunjung di Kalimantan Timur. Media Litbang Kesehatan. Vol. 20 No. 3 : 104-112.
Setyowati, R., Sudarsono, & Setyowati, E.P. 2014. The Effect of Water-Soluble Stem Extract “Kayu Kuning” (Arcangelisia flava L. Merr) on The Growth Inhibition of Candida albicans ATCC 10231 and Trichophyton mentagrophytes In Vitro. Biology, Medicine, & Natural Product Chemistry. Vol. 3 No. 1 : 17 – 22.
Sun, Y., Xun, K., Wang, Y., & Chen, X. 2009. A Systematic Review of The Anticancer Properties of Berberine, a Natural Product from Chinese Herbs. Anti-Cancer Drugs. Vol. 20 : 757 – 769.
Werdhasari, A. 2014. Peran antioksidan bagi kesehatan. Jurnal Biotek Medisina Indonesia. Vol. 3 No. 2 : 59 – 68.
Widi, R.K. & Indriati, T. 2007. Penjaringan dan Identifikasi Senyawa Alkaloid dalam Batang Kayu Kuning (Arcangelisia flava Merr). Jurnal Ilmu Dasar. Vol. 8 No. 1 : 24 – 29.
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Published
2019-02-22
How to Cite
Suratno, S., Rizki, M. I., & Pratama, M. R. F. (2019). In-Vitro Study of Antioxidant Activities from Ethanol Extracts of Akar Kuning (Arcangelisia flava). Jurnal Surya Medika (JSM), 4(2), 66–71. https://doi.org/10.33084/jsm.v4i2.594
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