Utilization of Catechins in Sunscreen Lotion Formulation
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Catechins, Gambir, Uncaria gambir Roxb, Lotion, Sunscreen
Abstract
Skin is the outermost part of the body which is susceptible to solar radiation. Excessive radiation from ultraviolet (UV) rays can harm the skin, such as premature aging effect, erythema, and even skin cancer. Antioxidant compounds are needed to protect the skin from excessive exposure of UV rays. The antioxidant can be useful as a defense system against free radicals, ultraviolet radiation, and air pollution. One source of antioxidant from nature is Catechins. Catechins are obtained from the isolation of gambir (Uncaria gambir Roxb). Besides being useful as an antioxidant, Catechins also has antibacterial, antiseptic and wound healing effect. The antioxidant activity of Catechins can absorb UV rays, provides protection against oxidative stress, inflammation, and skin cancer. Therefore, the research is necessary to utilize the catechins in sunscreen lotion formulation. Catechins are isolated from gambir by maceration with hexane and ethyl acetate (polar, nonpolar and residual fractions). The fraction which yields the most catechins is used as the active substance in the formulation. The formulation is divided into 4 lotion formulas, namely Formula 1 with 0.5% catechins concentration, Formula 2 with 7.5% catechins concentration, Formula 3 with 1% catechins concentration, and Formula 4 without catechins substance. Physical stability test and effectiveness of sunscreen formulation are carried out on 4 lotion formulas. Physical stability tests included organoleptic observation, homogeneity, pH, and assessment of the effectiveness of sunscreen formulation by using UV-Vis Spectrophotometer.
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References
Isnawati, A., Raini, M., Sampurno, O.D., Mutiatikum, D., Widowati, L., Gitawati, R., 2012. Karakterisasi Tiga Jenis Ekstrak Gambir (Uncaria gambir Roxb) dari Sumatera Barat. Buletin Penelitian Kesehatan. 40(4):201-208
Lobo, V., Patil, Chandra, N., 2010. Free Radical, Antioxidants and Functional Food: Impact of Human Health. Pharmacognosy Review. 4(8):118-126.
Mackiewicz, L., Rimkevicius, A. 2008. Aging Skin. Gerontologija. 9(2):103-108.
Mansur, J.S., Breeder, M.N., Azulay, R.D. 1986. Determinação do Fator de proteção diesel por espectrofotometria. Anais Brasileiros de Dermalogia, 61:121-24
Purwaningsih, S., Salamah, E., Adnin, M.N., 2015. Securities photoprotective Sunscreen Cream with Addition of carrageenan and Black Mangrove fruit (Rhizophora mucronata Lamk.). Journal of Tropical Marine Science and Technology. 7(1):1-14.
Sa'adah, L. 2010. Isolation and Identification of Compounds Tannins from Daun Belimbing Wuluh (Averrhoa bilimbi L.). Skripsi. Malang: Department of Chemistry UIN Maulana Malik Ibrahim.
Sayre, R.M., Agin, P.P., Levee, G.J., Madowe, E. 1979. Comparison of In Vivo and In Vitro Testing of Sunscreening Formulas. Photochemistry and Photobiology. 29:559-566.
Shovyana, H.H., Zulkarnain, A.K. 2013. Physical Stability and Activity of Cream W / O Etanolic Fruit Extract of Mahkota Dewa (Phaleria macrocarpha (Scheff.) Boerl.) As a Sunscreen. Traditional Medicine Journal. 18(2):210-221.
Silvikasari, Wafa, N.I., Utami, O.Y., Nurhaeni, R., Faris, M. 2010. Uji Efektivitas Katekin Dari Daun Gambir (Uncaria gambir (Hunter) Roxb) Sebagai Bahan Alternatif Pengawet Tahu di Kabupaten Bogor. Skripsi. Bogor: Institut Pertanian Bogor.
Towaha, J. 2010. Catechin in Gambir and its role in Semi industry. Popular Spice and Industrial Plants. 1(17).
Winarsi, H. 2007. Natural Antioxidants and Free Radicals. Yogyakarta: Kanisius.
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Copyright (c) 2018 Sefrianita Kamal, Mesa Sukmadani Rusdi
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