Antioxidant Activity, Total Phenolics, and Total Flavonoids Content of Bajakah Tampala (Spatholobus littoralis): The Indigenous Herbal Medicine from Kalimantan

Nurkhasanah Mahfudh (1) , Habib Basyanur Murdi (2) , Dwi Utami (3) , Mustofa Ahda (4) , Siti Nashihah (5) , Andika Andika (6)
(1) Universitas Ahmad Dahlan , Indonesia
(2) Universitas Ahmad Dahlan , Indonesia
(3) Universitas Ahmad Dahlan , Indonesia
(4) Universitas Ahmad Dahlan , Indonesia
(5) Universitas Muhammadiyah Banjarmasin , Indonesia
(6) Universitas Muhammadiyah Banjarmasin , Indonesia

Abstract

Bajakah tampala (Spatholobus littoralis), a medicinal plant traditionally used in Indonesia, particularly on Kalimantan Island, has garnered interest for its potential health benefits. However, scientific evidence remains scarce. This study investigated the antioxidant activity of S. littoralis extract and its total phenolic and flavonoid content. Ethanol extraction and evaporation were used to prepare the extract. The DPPH method assessed antioxidant activity, while Folin–Ciocalteu and AlCl3 complexation methods quantified total phenolics and flavonoids, respectively. The S. littoralis extract exhibited strong antioxidant activity with an IC50 value of 54.19 ± 8.15 µg/mL. Additionally, the extract contained substantial levels of phenolics (0.649 ± 0.026% GAE) and flavonoids (1.084 ± 0.043% QE). These findings suggest a link between the high phenolic and flavonoid content of S. littoralis extract and its observed strong antioxidant activity.

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Authors

Nurkhasanah Mahfudh
nurkhas@gmail.com (Primary Contact)
Habib Basyanur Murdi
Dwi Utami
Mustofa Ahda
Siti Nashihah
Andika Andika
Author Biographies

Nurkhasanah Mahfudh, Universitas Ahmad Dahlan

Department of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Special Region of Yogyakarta, Indonesia

Habib Basyanur Murdi, Universitas Ahmad Dahlan

Department of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Special Region of Yogyakarta, Indonesia

Dwi Utami, Universitas Ahmad Dahlan

Department of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Special Region of Yogyakarta, Indonesia

Mustofa Ahda, Universitas Ahmad Dahlan

Department of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Special Region of Yogyakarta, Indonesia

Siti Nashihah, Universitas Muhammadiyah Banjarmasin

Department of Pharmacy, Universitas Muhammadiyah Banjarmasin, Barito Kuala, South Kalimantan, Indonesia

Andika Andika, Universitas Muhammadiyah Banjarmasin

Department of Pharmacy, Universitas Muhammadiyah Banjarmasin, Barito Kuala, South Kalimantan, Indonesia

1.
Mahfudh N, Murdi HB, Utami D, Ahda M, Nashihah S, Andika A. Antioxidant Activity, Total Phenolics, and Total Flavonoids Content of Bajakah Tampala (Spatholobus littoralis): The Indigenous Herbal Medicine from Kalimantan. Borneo J Pharm [Internet]. 2024Aug.30 [cited 2024Dec.10];7(3):247-53. Available from: https://journal.umpr.ac.id/index.php/bjop/article/view/6609

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