Potential of Indonesian Plants as Polymicrobial Anti-Biofilm

Rafika Sari (1) , Sylvia Utami Tunjung Pratiwi (2) , Yosi Bayu Murti (3) , Ema Damayanti (4)
(1) Tanjungpura University , Indonesia
(2) Universitas Gadjah Mada , Indonesia
(3) Universitas Gadjah Mada , Indonesia
(4) National Research and Innovation Agency , Indonesia

Abstract

Biofilm infection occurs in 80% of chronic infections caused by 60% of biofilms from plankton cells and polymicrobial biofilms. Due to synergistic interactions between species, infections caused by polymicrobial biofilms are more virulent than monospecies biofilm infections. New anti-biofilm candidates are constantly being developed by tracing the content of active compounds from medicinal plants native to Indonesia. The need to find new plant sources that have the potential as anti-biofilms is increasingly needed along with increasing microbial resistance. Various studies show that active compounds that have anti-biofilm potential are polyphenols, quercetin, curcumin, gallic acid, and ferulic acid. The mechanism of action of anti-biofilms is through the prevention of attachment and formation of biofilms, inhibition of quorum sensing, and inhibition of gene expression in microbes.

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References

1. Aslam B, Wang W, Arshad MI, Khurshid M, Muzammil S, Rasool MH, et al. Antibiotic resistance: a rundown of a global crisis. Infect Drug Resist. 2018;11:1645-58. DOI: 10.2147/idr.s173867; PMCID: PMC6188119; PMID: 30349322
2. Dostert M. Antibiofilm peptides: overcoming biofilm-related treatment failure. RSC Adv. 2021;11(5):2718–28. DOI: 10.1039/d0ra09739j; PMCID: PMC8694000; PMID: 35424252
3. Amankwah S, Abdella K, Kassa T. Bacterial Biofilm Destruction: A Focused Review on the Recent Use of Phage-Based Strategies with Other Antibiofilm Agents. Nanotechnol Sci Appl.2021;14:161-77. DOI: 10.2147/nsa.s325594; PMCID: PMC8449863; PMID: 34548785
4. Preda VG, Săndulescu O. Communication is the key: biofilms, quorum sensing, formation and prevention. Discoveries. 2019;7(3):e100. DOI: 10.15190/d.2019.13; PMCID: PMC7086079; PMID: 32309618
5. Anju VT, Busi S, Imchen M, Kumavath R, Mohan MS, Salim SA, et al. Polymicrobial Infections and Biofilms: Clinical Significance and Eradication Strategies. Antibiotics. 2022;11(12):1731. DOI: 10.3390/antibiotics11121731; PMCID: PMC9774821; PMID: 36551388
6. Orazi G, O'Toole GA. "It Takes a Village": Mechanisms Underlying Antimicrobial Recalcitrance of Polymicrobial Biofilms. J Bacteriol. 2019;202(1):e00530-19. DOI: 10.1128/jb.00530-19; PMCID: PMC6932244; PMID: 31548277
7. Sartini S, Permana AD, Mitra S, Tareq AM, Salim E, Ahmad I, et al. Current State and Promising Opportunities on Pharmaceutical Approaches in the Treatment of Polymicrobial Diseases. Pathogens. 2021;10(2):245. DOI: 10.3390/pathogens10020245
8. Rodrigues ME, Gomes F, Rodrigues CF. Candida spp./Bacteria Mixed Biofilms. J Fungi. 2019;6(1):5. DOI: 10.3390/jof6010005; PMCID: PMC7151131; PMID: 31861858
9. Gabrilska RA, Rumbaugh KP. Biofilm models of polymicrobial infection. Future Microbiol. 2015;10(12):1997-2015. DOI: 10.2217/fmb.15.109; PMCID: PMC4944397; PMID: 26592098
10. Dutt Y, Dhiman R, Singh T, Vibhuti A, Gupta A, Pandey RP, et al. The Association between Biofilm Formation and Antimicrobial Resistance with Possible Ingenious Bio-Remedial Approaches. Antibiotics. 2022;11(7):930. DOI: 10.3390/antibiotics11070930; PMCID: PMC9312340; PMID: 35884186
11. Salam MA, Al-Amin MY, Salam MT, Pawar JS, Akhter N, et al. Antimicrobial Resistance: A Growing Serious Threat for Global Public Health. Healthcare. 2023;11(13):1946. DOI: 10.3390/healthcare11131946; PMCID: PMC10340576; PMID: 37444780
12. Abdallah EM, Alhatlani BY, Menezes RdP, Martins CHG. Back to Nature: Medicinal Plants as Promising Sources for Antibacterial Drugs in the Post-Antibiotic Era. Plants. 2023;12(17):3077. DOI: 10.3390/plants12173077; PMCID: PMC10490416; PMID: 37687324
13. Cleary DFR, DeVantier L. Indonesia: Threats to the Country's Biodiversity. In: Nriagu JO, editor. Encyclopedia of Environmental Health. Amsterdam: Elsevier Science; 2011. p. 187-97. DOI: 10.1016/B978-0-444-52272-6.00504-3
14. Setiawan A. Keanekaragaman Hayati Indonesia: Masalah dan Upaya Konservasinya. Indones J Conserv. 2022;11(1):13-21. DOI: 10.15294/ijc.v11i1.34532
15. Arozal W, Louisa M, Soetikno V. Selected Indonesian Medicinal Plants for the Management of Metabolic Syndrome: Molecular Basis and Recent Studies. Front Cardiovasc Med. 2020;7:82. DOI: 10.3389/fcvm.2020.00082; PMCID: PMC7218133; PMID: 32435657
16. Arisanti IP, Yamasari Y. Mengenali Jenis Tanaman Obat Berbasis Pola Citra Daun Dengan Algoritma K-Nearest Neighbors. J Informatics Comput Sci 2021;3(2):95-103. DOI: 10.26740/jinacs.v3n02.p95-103
17. Pangastuti A, Sari SLA, Budiharjo A, Fitri ST, Sayekti P, Putri SR. Screening of some Indonesian medicinal plant extracts for anti quorum sensing activity to prevent Aeromonas hydrophila infection on Oreochromis niloticus. Biodiversitas. 2021;22(8):3517-22. DOI: 10.13057/biodiv/d220851
18. Fitria A. The Bactericidal and Antibiofilm Activity of Stem Bark of Jatropha multifida L. Against Staphylococcus aureus and MRSA. Eksakta J Sci Data Anal. 2018;18(1):42–55. DOI: 10.20885/eksakta.vol18.iss1.art5
19. Zhao A, Sun J, Liu Y. Understanding bacterial biofilms: From definition to treatment strategies. Front Cell Infect Microbiol. 2023;13:1137947. DOI: 10.3389/fcimb.2023.1137947; PMCID: PMC10117668; PMID: 37091673
20. Sharma S, Mohler J, Mahajan SD, Schwartz SA, Bruggema L, Aalinkeel R. Microbial Biofilm: A Review on Formation, Infection, Antibiotic Resistance, Control Measures, and Innovative Treatment. Microorganisms. 2023;11(6):1614. DOI: 10.3390/microorganisms11061614; PMCID: PMC10305407; PMID: 37375116
21. Prazdnova E, Gorovtsov AV, Vasilchenko NG, Kulikov MP, Statsenko VN, Bogdanova AA, et al. Quorum-Sensing Inhibition by Gram-Positive Bacteria. Microorganisms. 2022;10(2):350. DOI: 10.3390/microorganisms10020350; PMCID: PMC8875677; PMID: 35208805
22. Hrynyshyn A, Simões M, Borges A. Biofilms in Surgical Site Infections: Recent Advances and Novel Prevention and Eradication Strategies. Antibiotics. 2022;11(1):69. DOI: 10.3390/antibiotics11010069; PMCID: PMC8773207; PMID: 35052946
23. Jamal M, Ahmad W, Andleeb S, Jalil F, Imran M, Nawaz MA, et al. Bacterial biofilm and associated infections. J Chin Med Assoc. 2018;81(1):7-11. DOI: 10.1016/j.jcma.2017.07.012; PMID: 29042186
24. Manner S, Fallarero A. Screening of Natural Product Derivatives Identifies Two Structurally Related Flavonoids as Potent Quorum Sensing Inhibitors against Gram-Negative Bacteria. Int J Mol Sci. 2018;19(5):1346. DOI: 10.3390/ijms19051346; PMCID: PMC5983823; PMID: 29751512
25. Rather MA, Gupta K, Mandal M. Microbial biofilm: formation, architecture, antibiotic resistance, and control strategies. Braz J Microbiol. 2021;52(4):1701-18. DOI: 10.1007/s42770-021-00624-x; PMCID: PMC8578483; PMID: 34558029
26. Bowen WH, Burne RA, Wu H, Oral Biofilms: Pathogens, Matrix, and Polymicrobial Interactions in Microenvironments. Trends Microbiol. 2018;26(3):229–42. DOI: 10.1016/j.tim.2017.09.008; PMCID: PMC5834367; PMID: 29097091
27. Pratiwi SUT, Lagendijk EL, Hertiani T, de Weert S, van den Hondel CAMJJ. Antimicrobial effects of Indonesia medicinal plants extracts on planktonic and biofilm growth of Psedomonas aeruginosa and Staphylococcus aureus. J Hortic. 2015;2(1):1000119. DOI: 10.4172/2376-0354.1000119
28. Hertiani T, Pratiwi SUT, Irianto IDK, Adityaningrum D, Pranoto B. Effect of Indonesian medicinal plants essential oils on Streptococcus mutans biofilm. Indones J Pharm. 2011;22(3):174–81. DOI: 10.14499/indonesianjpharm0iss0pp174-181
29. Kining E, Falah S, Nurhidayat N. The in vitro antibiofilm activity of water leaf extract of papaya (Carica papaya L) against Pseudomonas aeruginosa. Curr Biochem 2016;2(3):150–63. DOI: 10.29244/cb.2.3.150-163
30. Gracia E, Magdalena S, Wina E, Sinurat AP, Purwadaria T. Plant extract as antioxidant and antibiofilm against chicken gut bacteria. J Ilmu Ternak Vet. 2018;23(1):11–7. DOI: 10.14334/jitv.v23i1.1800
31. Hamzah H, Hertiani T, Pratiwi SUT, Nuryastuti T. Inhibitory activity and degradation of curcumin as antibiofilm polymicrobial on catheters. Int J Res Pharm Sci. 2020;11(1):830–5. DOI: 10.26452/ijrps.v11i1.1902
32. Hamzah H, Rasdianah N, Nurwijayanto A, Nandini E. Aktivitas ekstrak etanol daun calincing terhadap biofilm Candida albicans. J Farmasetis. 2021;10(1):21–8. DOI: 10.32583/farmasetis.v10i1.1319
33. Tobi CHB, Saptarini O, Rahmawati I. Aktivitas Antibiofilm Ekstrak dan Fraksi-Fraksi Biji Pinang (Areca catechu L.) Terhadap Staphylococcus aureus ATCC 25923. J Pharm Sci Clin Res. 2022;7(1):56–70. DOI: 10.20961/jpscr.v7i1.43698
34. Wahabi AIS. Pengaruh Ekstrak Biji Kepayang (Pangium edule Reinw.) terhadap Destruksi Biofilm Bakteri Streptococcus sanguinis ATCC 10556 [bachelor’s thesis]. Yogyakarta: Universitas Gadjah Mada; 2022. Available from: https://etd.repository.ugm.ac.id/penelitian/detail/210344
35. Wirasisya DG. Aktivitas Antibakteri dan Antibiofilm Ekstrak Etanolik dan Fraksi Larut Metanol Umbi Bawang Tiwai (Eleutherine americana. Merr) pada Isolat Klinis Staphylococcus aureus [bachelor’s thesis]. Yogyakarta: Universitas Gadjah Mada; 2014. Available from: https://etd.repository.ugm.ac.id/home/detail_pencarian/74306
36. Rahmaningtyas AN. Pengaruh Ekstrak Etanol Biji Ketumbar (Coriandrum sativum L) Terhadap Penghambatan Pembentukan Biofilm Streptococcus mutans ATCC 25175 in Vitro [bachelor’s thesis]. Yogyakarta: Universitas Gadjah Mada; 2021. Available from: https://etd.repository.ugm.ac.id/penelitian/detail/207004
37. Simangasing NA. Pengaruh Ekstrak Daun Nangka (Artocarpus Heterophyllus) terhadap Destruksi Biofilm Streptococcus sanguinis ATCC 10556 In Vitro [bachelor’s thesis]. Yogyakarta: Universitas Gadjah Mada; 2021. Available from: https://etd.repository.ugm.ac.id/penelitian/detail/206831
38. Ardani M, Pratiwi SUT, Hertiani T. Effect of cengkeh leaves and kayu manis cortex essential oils blend as anti dental plaque. Indones J Pharm, 2010;21(3):191–201. DOI: 10.14499/indonesianjpharm0iss0pp191-201
39. Kining E, Falah S, Nurhidayat N. Aktivitas Antibiofilm Ekstrak Air Daun Melinjo, Daun Singkong, Dan Daun Pepaya Terhadap Bakteri Pseudomonas Aeruginosa Secara In Vitro [master’s thesis]. Bogor: IPB University; 2015. Available from: http://repository.ipb.ac.id/handle/123456789/78746
40. Rollando R, Prasetyo YSA, Sitepu R. Uji Antimikroba Minyak Atsiri Masoyi (Massoia aromatica) terhadap Bakteri Streptococcus mutans. Majalah Farmasi Farmakologi. 2019;23(2):52–7. DOI: 10.20956/mff.v23i2.6585
41. Pratiwi SUT, Lagendijk EL, de Weert S, Idroes R, Hertiani T, van den Hondel C. Effect of Cinnamomum burmannii Nees ex Bl. and Massoia aromatica Becc. Essential Oils on Planktonic Growth and Biofilm formation of Pseudomonas aeruginosa and Staphylococcus aureus In Vitro. Int J Appl Res Nat Prod. 2015;8(2):1–13.
42. Hamzah H, Nuryastuti T, Rahmah W, Chabib L, Syamsul ES, Lestari D, et al. Molecular Docking Study of the C-10 Massoia Lactone Compound as an Antimicrobial and Antibiofilm Agent against Candida tropicalis. ScientificWorldJournal. 2023;2023:6697124. DOI: 10.1155/2023/6697124; PMCID: 10522437; PMID: 37766863
43. Utami DT, Pratiwi SUT, Spaink HP, Haniastuti T, Hertiani T. Antibiofilm effect of C-10 massoia lactone toward polymicrobial oral biofilms. J Adv Pharm Technol Res. 2021;12(1):89-93. DOI: 10.4103/japtr.japtr_105_20; PMCID: 7832195; PMID: 33532362
44. Tabunhan S, Tungsukruthai P. Antibiofilm Activity of a Curcuma zedoaria Rosc Rhizome Extract against Methicillin-Resistant and Susceptible Staphylococcus aureus. Microbiol Biotechnol Lett. 2022;50(2):193–201. DOI: 10.48022/mbl.2201.01007
45. Syamsunarno MRA, Safitri R, Kamisah Y. Protective Effects of Caesalpinia sappan Linn. and Its Bioactive Compounds on Cardiovascular Organs. Front Pharmacol. 2021;12:725745. DOI: 10.3389/fphar.2021.725745; PMCID: PMC8479160; PMID: 34603037
46. Batubara I, Mitsunaga T, Ohashi H. Brazilin from Caesalpinia sappan wood as an antiacne agent. J Wood Sci. 2010;56:77-81. DOI: 10.1007/s10086-009-1046-0
47. Utami TW, Ekananda BN, Anjani YR, Listyarifah D, Nur A, Syahbudin A. Comparison Effect of Leaves and Bark Extract of Eucalyptus (Melaleuca leucadendra), Sappan (Caesalpinia sappan), and Cinnamon (Cinnamomum zeylanicum) to Reduce Streptococcus mutans Biofilm Formation. Majalah Kedokteran Gigi Indones. 2023;9(1):81. DOI: 10.22146/majkedgiind.83283
48. Nirmal NP, Rajput MS, Prasad RGSV, Ahmad M. Brazilin from Caesalpinia sappan heartwood and its pharmacological activities: A review. Asian Pac J Trop Med. 2015;8(6):421–30. DOI: 10.1016/j.apjtm.2015.05.014; PMID: 26194825
49. Al-Dhubiab BE. Pharmaceutical applications and phytochemical profile of Cinnamomum burmannii. Pharmacogn Rev. 2012;6(12):125-31. DOI: 10.4103/0973-7847.99946; PMCID: PMC3459454; PMID: 23055638
50. Foudah AI, Shakeel F, Alqarni MH, Ross SA, Salkini MA, Alam P. Simultaneous Estimation of Cinnamaldehyde and Eugenol in Essential Oils and Traditional and Ultrasound-Assisted Extracts of Different Species of Cinnamon Using a Sustainable/Green HPTLC Technique. Molecules. 2021;26(7):2054. DOI: 10.3390/molecules26072054; PMCID: PMC8038348; PMID: 33916710
51. Pratiwi SUT. Anti-microbial and anti-biofilm compounds from Indonesian medicinal plants [dissertation]. Leiden: Universiteit Leiden; 2015. Available from: https://hdl.handle.net/1887/36530
52. Muhamad KZ. Uji Aktivitas Antibakteri Ekstrak dan Fraksi Daun Sintok (Cinnamomun sintoc) terhadap Staphylococcus aureus dan Pseudomonas aeruginosa serta Analisa Kom[onen Senyawa Fraksi Aktif dengan Kromatografi Gas-Spektrometri Massa [bachelor’s thesis]. Jakarta: Universitas Islam Negeri Syarif Hidayatullah; 2014. Available from: http://repository.uinjkt.ac.id/dspace/handle/123456789/25844
53. Helmy YA, Taha-Abdelaziz K, Hawwas HAE, Ghosh S, AlKafaas SS, Moawad MMM, et al. Antimicrobial Resistance and Recent Alternatives to Antibiotics for the Control of Bacterial Pathogens with an Emphasis on Foodborne Pathogens. Antibiotics. 2023;12(2):274. DOI: 10.3390/antibiotics12020274; PMCID: PMC9952301; PMID: 36830185
54. Dash BK, Sen MK, Alam K, Hossain K, Islam R, Banu NA, et al. Antibacterial activity of Nymphaea nouchali (Burm. f) flower. Ann Clin Microbiol Antimicrob. 2013;12(1):27. DOI: 10.1186/1476-0711-12-27; PMCID: PMC3852100; PMID: 24099586
55. Alves DdN, Monteiro AFM, Andrade PN, Lazarini JG, Abílio GMF, Guerra FQS, et al. Docking Prediction, Antifungal Activity, Anti-Biofilm Effects on Candida spp., and Toxicity against Human Cells of Cinnamaldehyde. Molecules. 2020;25(24):5969. DOI: 10.3390/molecules25245969; PMCID: PMC7767272; PMID: 33339401
56. Firmino DF, Cavalcante TTA, Gomes GA, Firmino NCS, Rosa LD, de Carvalho MG, et al. Antibacterial and Antibiofilm Activities of Cinnamomum Sp. Essential Oil and Cinnamaldehyde: Antimicrobial Activities. ScientificWorldJournal. 2018;2018:7405736. DOI: 10.1155/2018/7405736; PMCID: PMC6011056; PMID: 29977171
57. Rahmat E, Lee J, Kang Y. Javanese Turmeric (Curcuma xanthorrhiza Roxb.): Ethnobotany, Phytochemistry, Biotechnology, and Pharmacological Activities. Evid Based Complement Alternat Med. 2021;2021:9960813. DOI: 10.1155/2021/9960813; PMCID: PMC8214482; PMID: 34194529
58. Kining E, Firdiani D, Sogandi, Aminullah, Asma S. Antibacterial and Antibiofilm Activity of Melinjo Leaf Water Extract against Pseudomonas aeruginosa Bacteria. Indones Nat Res Pharm J. 2022;7(1):19–31. DOI: 10.52447/inrpj.v7i1.5901
59. Kačániová M, Galovičová L, Borotová P, Valková V, Ďúranová H, Kowalczewski PŁ, et al. Chemical Composition, In Vitro and In Situ Antimicrobial and Antibiofilm Activities of Syzygium aromaticum (Clove) Essential Oil. Plants. 2021;10(10):2185. DOI: 10.3390/plants10102185; PMCID: PMC8538430; PMID: 34685994
60. Akbari S, Didar Z, Vazifedoost M, Hajirostamloo B, Mohtashami M. Antibiofilm Activity of Ginger (Zingiber officinale) Extracts In Vitro and Food Model. J Food Process Preserv 2023;2023:5134332. DOI: 10.1155/2023/5134332
61. Kunarti S, Ramadhani A, Setyowati L. Antibiofilm Activity of Mangosteen (Garcinia mangostana L.) Flavonoids against Streptococcus mutans Bacteria. Conserv Dent J 2020;10(2):48-50. DOI: 10.20473/cdj.v10i2.2020.48-50
62. Ribeiro SM, Fratucelli EDO, Bueno PCP, de Castro MKV, Francisco AA, Cavalheiro AJ, et al. Antimicrobial and antibiofilm activities of Casearia sylvestris extracts from distinct Brazilian biomes against Streptococcus mutans and Candida albicans. BMC Complement Altern Med. 2019;19(1):308. DOI: 10.1186/s12906-019-2717-z; PMCID: PMC6852947; PMID: 31718633
63. Triveni AG, Kumar MS, Shivannavar CT, Gaddad SM. Antibacterial and antibiofilm activities of crude extracts of Lawsonia inermis against methicillin-resistant Staphylococcus aureus. Asian J Pharm Clin Res. 2016;9(6):263–5. DOI: 10.22159/ajpcr.2016.v9i6.14362
64. Sahal G, Woerdenbag HJ, Hinrichs WLJ, Visser A, Tepper PG, Quax WJ, et al. Antifungal and biofilm inhibitory effect of Cymbopogon citratus (lemongrass) essential oil on biofilm forming by Candida tropicalis isolates; an in vitro study. J Ethnopharmacol. 2020;246:112188. DOI: 10.1016/j.jep.2019.112188; PMID: 31470085
65. Ambade SV, Deshpande NM. Antimicrobial and Antibiofilm Activity of Essential Oil of Cymbopogon citratus against Oral Microflora Associated with Dental Plaque. Eur J Med Plants. 2019;28(4):1–11. DOI: 10.9734/ejmp/2019/v28i430143
66. Wang YC, Hsu HW, Liao WL. Antibacterial activity of Melastoma candidum D. Don. LWT - Food Sci Technol. 2008;41(10):1793–8. DOI: 10.1016/j.lwt.2008.02.005
67. Omar SNC, Abdullah JO, Khairoji KA, Chin SC, Hamid M. Effects of Flower and Fruit Extracts of Melastoma malabathricum Linn. on Growth of Pathogenic Bacteria: Listeria monocytogenes, Staphylococcus aureus, Escherichia coli, and Salmonella typhimurium. Evidence-Based Complement Altern Med. 2013;2013:459089. DOI: 10.1155/2013/459089; PMCID: PMC3638579; PMID: 23662136
68. Sufian AS, Ramasamy K, Ahmat N, Zakaria ZA, Yusof MIM. Isolation and identification of antibacterial and cytotoxic compounds from the leaves of Muntingia calabura L. J Ethnopharmacol. 2013;146(1):198–204. DOI: 10.1016/j.jep.2012.12.032; PMID: 23276785
69. MosaChristas K, Kowsalya E, Karthick R, Jaquline CRI. Antibacterial, antibiofilm and anti-quorum sensing activities of Muntingia calabura L. leaf extract against Pseudomonas aeruginosa. Lett Appl Microbiol. 2022;75(3):588–97. DOI: 10.1111/lam.13595; PMID: 34725846
70. Di Salle A, Viscusi G, Di Cristo F, Valentino A, Gorrasi G, Lamberti E, et al. Antimicrobial and Antibiofilm Activity of Curcumin-Loaded Electrospun Nanofibers for the Prevention of the Biofilm-Associated Infections. Molecules. 2021;26(16):4866. DOI: 10.3390/molecules26164866; PMCID: PMC8400440; PMID: 34443457
71. Hamzah H, Siregar KAAK, Nurwijayanto A, Wahyuningrum R, Sari S. Effectiveness of Oxalis corniculata L. Ethanol Extract against Mono-Species of Biofilm Staphylococcus aureus. Borneo J Pharm. 2021;4(3):184–91. DOI: 10.33084/bjop.v4i3.2418
72. Sari LM, Hakim RF, Mubarak Z, Andriyanto A. Analysis of phenolic compounds and immunomodulatory activity of areca nut extract from Aceh, Indonesia, against Staphylococcus aureus infection in Sprague-Dawley rats. Vet World. 2020;13(1):134-40. DOI: 10.14202/vetworld.2020.134-140; PMCID: PMC7020107; PMID: 32158163
73. Firdausi A, Siswoyo TA, Wiryadiputra S. Identification of Potential Plants Producing Tannin-protein Complex for
-amylase as Botanical Pesticide. Pelita Perkebunan. 2013;29(1):31–43. DOI: 10.22302/iccri.jur.pelitaperkebunan.v29i1.189
74. Keyvani-Ghamsari S, Rahimi M, Khorsandi K. An update on the potential mechanism of gallic acid as an antibacterial and anticancer agent. Food Sci Nutr. 2023;11(10):5856-72. DOI: 10.1002/fsn3.3615; PMCID: PMC10563697; PMID: 37823155
75. Sutomo S, Pratama MRF. Measuring the potential antioxidant activity of methyl gallate: Molecular docking study. Thai J Pharm Sci. 2019;44(1):14-22.
76. Rollando R. Isolasi, Identifikasi, Karakterisasi, dan Uji Antibiofilm Derivat Asam Galat dari Kulit Batang Sterculia quadrifida R.Br. J Kefarmasian Indones. 2017;7(2):105–11.
77. Karo-karo SU, Arianto A, Salim E. Antibacterial Activity and Determination of Total Phenol and Flavonoid of Carica papaya L. Ethanol Extract. Int J Sci Technol Manag. 2023;4(1):233-8. DOI: 10.46729/ijstm.v4i1.738
78. Singh SP, Kumar S, Mathan SV, Tomar MS, Singh RK, Verma PK, et al. Therapeutic application of Carica papaya leaf extract in the management of human diseases. Daru. 2020;28(2):735-44. DOI: 10.1007/s40199-020-00348-7; PMCID: PMC7704890; PMID: 32367410
79. Borges A, Saavedra M, Simões M. The activity of ferulic and gallic acids in biofilm prevention and control of pathogenic bacteria. Biofouling. 2012;28(7):755–67. DOI: 10.1080/08927014.2012.706751; PMID: 22823343
80. Dasagrandhi C, Park S, Jung WK, Kim YM. Antibacterial and Biofilm Modulating Potential of Ferulic Acid-Grafted Chitosan against Human Pathogenic Bacteria. Int J Mol Sci. 2018;19(8):2157. DOI: 10.3390/ijms19082157; PMCID: PMC6121546; PMID: 30042337
81. Makagansa C, Mamuaja CF, Mandey LC. The Antibacterial Activity of Pangi Kernel Extract (Pangium Edule Reinw) Towards Staphylococcus Aureus, Bacillus Cereus, Pseudomonas Aeruginosa and Escherichia Coli in Vitro. J Ilmu Teknologi Pangan. 2015;3(1):16–20.
82. Kamarudin AA, Sayuti NH, Saad N, Razak NAA, Esa NM. Eleutherine bulbosa (Mill.) Urb. Bulb: Review of the Pharmacological Activities and Its Prospects for Application. Int J Mol Sci. 2021;22(13):6747. DOI: 10.3390/ijms22136747; PMCID: PMC8268349; PMID: 34201683
83. Pratama MRF, Aziz IR. Molecular Docking of Bawang Dayak (Eleutherine bulbosa) Secondary Metabolites as Bacterial Cell Wall Synthesis Inhibitor. In: Harini S, Hafsan, Sahara, Aziz IR, Rahim R, editors. 1st International Conference on Science and Technology, ICOST 2019, 2-3 May, Makassar, Indonesia. Gent: European Alliance for Innovation; 2019. p. 1-11. DOI: 10.4108/eai.2-5-2019.2284686
84. Molina RDI, Campos-Silva R, Macedo AJ, Blázquez MA, Alberto MR, Arena ME. Antibiofilm activity of coriander (Coriander sativum L.) grown in Argentina against food contaminants and human pathogenic bacteria. Ind Crops Prod. 2020;151:112380. DOI: 10.1016/j.indcrop.2020.112380
85. Tripathi K, Kumar P, Kumar R, Saxena R, Kumar A, Badoni H, et al. Efficacy of jackfruit components in prevention and control of human disease: A scoping review. J Educ Health Promot. 2023;12:361. DOI: 10.4103/jehp.jehp_1683_22; PMCID: PMC10743863; PMID: 38144022
86. Khan MR, Omoloso AD, Kihara M. Antibacterial activity of Artocarpus heterophyllus. Fitoterapia. 2003;74(5):501–5. DOI: 10.1016/s0367-326x(03)00120-5; PMID: 12837372
87. Sato M, Fujiwara S, Tsuchiya H, Fujii T, Iinuma M, Tosa H, et al. Flavones with antibacterial activity against cariogenic bacteria. J Ethnopharmacol. 1996;54(2–3):171–6. DOI: 10.1016/s0378-8741(96)01464-x; PMID: 8953432
88. Ningsih I, Rosalinda DA, Kiranasari A, Dewi BE, Sjatna F. In Vitro Antibacterial Activity Test of Jackfruit (Artocarpus heterophyllus Lam.) Leaf Extract against Methicillin-Resistant Staphylococcus aureus (MRSA). In: Proceeding of the Bromo Conference Symposium on Natural Products and Biodiversity, 11-12 July 2018 Surabaya, East Java, Indonesia. Setúba: SciTePress; 2018. p. 1-5. DOI: 10.5220/0008360702450249
89. Ginting EV, Retnaningrum E, Widiasih DA. Antibacterial activity of clove (Syzygium aromaticum) and cinnamon (Cinnamomum burmannii) essential oil against extended-spectrum β-lactamase-producing bacteria. Vet World. 2021;14(8):2206–11. DOI: 10.14202/vetworld.2021.2206-2211; PMCID: PMC8448639; PMID: 34566340

Authors

Rafika Sari
Sylvia Utami Tunjung Pratiwi
sylvia_pratiwi@ugm.ac.id (Primary Contact)
Yosi Bayu Murti
Ema Damayanti
Author Biographies

Rafika Sari, Tanjungpura University

Doctoral Student in Pharmacy Science, Universitas Gadjah Mada, Sleman, Special Region of Yogyakarta, Indonesia

Department of Pharmacy, Universitas Tanjungpura, Pontianak, West Kalimantan, Indonesia

Sylvia Utami Tunjung Pratiwi, Universitas Gadjah Mada

Department of Pharmaceutical Biology, Universitas Gadjah Mada, Sleman, Special Region of Yogyakarta, Indonesia

Yosi Bayu Murti, Universitas Gadjah Mada

Department of Pharmaceutical Biology, Universitas Gadjah Mada, Sleman, Special Region of Yogyakarta, Indonesia

Ema Damayanti, National Research and Innovation Agency

Research Center for Food Processing and Technology, National Research and Innovation Agency of the Republic of Indonesia, Gunungkidul, Special Region of Yogyakarta, Indonesia

1.
Sari R, Pratiwi SUT, Murti YB, Damayanti E. Potential of Indonesian Plants as Polymicrobial Anti-Biofilm. Borneo J Pharm [Internet]. 2024Feb.29 [cited 2024May2];7(1):63-79. Available from: https://journal.umpr.ac.id/index.php/bjop/article/view/5645

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