Perbandingan Kadar HB Sebelum dan Sesudah Pengobatan Oat Fase Intensif pada Penderita Tuberkulosis Paru di Puskesmas Petanahan Kebumen Tahun 2021
The Comparison of Hemoglobin Levels Between Before and After Treatment of Intensive Phase of Anti-Tuberculosis Drug in Pulmonary Tuberculosis Patients of Petanahan Public Health Care Center, Kebumen Regency
DOI:
https://doi.org/10.33084/jsm.v9i1.5192Keywords:
Hemoglobin, OAT fase intensif, Tuberkulosis paruAbstract
Treatment of tuberculosis with main anti-tuberculosis drugs (OAT) includes isoniazid (INH), rifampin (RIF), ethambutanol (EMB), streptomycin (SM), and pyrazinamide (PZA). Although most Anti-Tuberculosis Drugs (OAT) are acceptable in therapy, they have potential side effects, including the side effects of hematological reactions such as anemia. This study's purpose was to compare HB levels before and after the intensive phase of Anti-Tuberculosis Drugs treatment in TB patients at Petanahan Public Health Care Center, Kebumen Regency. This was an analytic observational study with a cross-sectional design. The sample in this study was 28 people. The result showed that the average Hb level of pulmonary TB patients at Petanahan Public Health Care Center before and after the treatment were 11.05 g/dl and 11.6 g/dl, respectively. Therefore there was an effect of comparing Hb levels before and after the intensive phase of Anti-Tuberculosis Drugs treatment in pulmonary TB patients at the Petanahan Public Health Center in 2021. The increase in the average Hb levels of patients with pulmonary TB before and after the treatment was 0.55. The sig values obtained from the analysis of Hb levels before and after the treatment were a = 0.200 (p0.005) and 0.023, respectively. Due to the P value (0.023 < 0.05), Ho was rejected. It meant that there was a difference in Hb levels before and after the Intensive Phase of Anti-Tuberculosis Drugs treatment in patients with pulmonary TB at Petanahan Public Health Care Center, Kebumen Regency.
Downloads
References
Adang, Ulfi, Deta Noorfaizah. 2014. Perbedaan Kadar Hemoglobin Sebelum dan Sesudah Pemberian Obat Anti Tuberkulosis Fase Awal Program Studi Pendidikan Dokter. Yogyakarta: Fakultas Kedokteran dan Ilmu Kesehatan Universitas Muhammadiyah Yogyakarta.
Anggraini, L 2015. Status Gizi Vegetarian dan Vegan Pada Komunitas I Vegetarian di Yogyakarta (Kajian pada Lacto Ovo Vegetarian dan Vegan Terhadap Status IMT, Hemoglobin, Feritin, dan Protein. Jurnal Gizi Klinik Indonesia 2015.
Aziz Ni’ma N, Hasnah, Fatmawati. 2019. Studi Kadar Hemoglobin Pada Penderita Tuberculosis (TBC). Makasar: Politeknik Kesehatan Muhammadiyah Makassar.
Damayanti Sialagan. 2017. Pengaruh Asupan Fe, Vitamin A, Vitamin B12, Vitamin C Terhadap Kadar Hemoglobin Pada Remaja Vegan. Universitas Esa Unggul, Jurusan Ilmu Gizi. 2017.
Dinas Kesehatan Provinsi Jawa Tengah. 2020. Buku Saku Untuk Kader Kesehatan. Semarang: Dinas Kesehatan Provinsi Jawa Tengah.
Dinkes Kabupaten Kebumen. 2021. Analisa Situasi TB Kabupaten Kebumen. Kebumen: Dinkes Kabupaten Kebumen.
Istiantoro & Setiabudy. 2012. Farmakologi dan Terapi 5th ed. Jakarta: Fakultas Kedokteran Universitas Indonesia.
Kassa E, Enagaw B, Gelaw A, Gelaw B. 2014. Effect of Anti Tuberculosis Drugs on Hematological profiles of Tuberculosis Patients Attending at University of Gondar Hospital, Northwest Ethiopia, Norwest Ethiopia, BMC. Hematplogy.
Kementrian Kesehatan RI. 2020. Starategi Nasional Penaggulangan Tuberkulosis di Indonesia 2020 - 2024. Jakarta: Kementrian Kesehatan RI.
Lasut. 2014. Gambaran Kadar Hemoglobin dan Tromnbosit Pada Pasien Tuberkulosis Paru di RSUP Prof.DR.R.D. Kandou Manado Periode Januari sampai Desember 2014. Ringkasan Penelitian. Manado, Sam Ratulangi.
Lee, S.W., Kang,Y.A, Yoon,Y.S., Sang-Won, U., Lee, S.M., Chul-Gyu, Y., Kim, Y.W.,Han, S.K., Young-Soo, S., Jae-Joon, Y. 2016. The Prevalence and Evolution ofAnemia Associated with Tuberculosis Tuberculosis. J Korean Med Sci. 21 :1028–1032
Muwakhidah. 2019. Efek suplementasi fe, asam folat dan vitamin b 12 terhadap peningkatan kadar hemoglobin (hb) pada pekerja wanita di Kabupaten Sukoharjo. Jurnal Penelitian Sains & Teknologi: Vol. 11, No. 1, April 2019: 11 – 18.
Natalie. 2016. Jenis-Jenis efek samping pengobatan OAT dan ART di RSUP.DR. Kariadi. Semarang
Oehadian, 2019. Aspek Hematologi Tuberkulosis. Bandung: FK UNPAD Bandung.
Puskesmas Petanahan. 2021. Analisa Situasi TB Kecamatan Petanahan. Kebumen: Puskesmas Petanahan.
Sediaoetama, AD. 2018. Ilmu Gizi jilid II. Jakarta: Dian Rakyat.
Supariasa, I. D., Bachyar Bakri., Ibnu F. 2016. Penilaian Status Gizi. Jakarta: Penerbit Buku Kedokteran ECG.
Syarifah Khairsani. 2017. Gambaran Jumlah Leukosit dan Jenis Leukosit Pada Pasien Tuberkulosis Paru Sebelum Pengobatan Dengan Setelah Pengobatan Satu Bulan Intensif di Puskesmas Pekanbaru. Pekanbaru.
World Health Organisation. 2020. Global Tuberculosis Report 2020.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Evi Nurhayati, Arif Mulyanto, Tantri Analisawati Sudarsono, Linda Wijaya
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
All rights reserved. This publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording.