Effectiveness of Digital Pharmaceutical Care Intervention on Medication Adherence in Hypertensive Patients: A Quasi-Experimental Study in Banjarmasin, South Kalimantan

Authors

DOI:

https://doi.org/10.33084/bjop.v9i3.12742

Keywords:

Healthcare, Hypertension, medication adherence, mHealth, Community Pharmacy

Abstract

Hypertension remains a major public health challenge in Indonesia, where suboptimal adherence to antihypertensive therapy contributes to poor blood pressure control and avoidable cardiovascular risk. Pharmacist-led digital care offers a promising strategy to enhance medication adherence. This study aimed to evaluate the effectiveness of SatuObat, a Pharmacist-led digital care app, in improving medication adherence among hypertensive patients in community pharmacy practice. A quasi-experimental study with a non-equivalent control group pre-test and post-test design was conducted at community pharmacies in Banjarmasin, Indonesia. A total of 102  patients were recruited using consecutive sampling and assigned to either a control group (receiving usual care, n=52) or an intervention group (receiving usual care plus SatuObat app, n=50). The intervention comprised structured digital reminders, two-way chat with pharmacists, and tailored educational messages delivered through the app over 4 weeks. Medication adherence was measured using the validated Indonesian version of the MARS-5 questionnaire. Data were analyzed using the Wilcoxon signed-rank test and the Mann-Whitney U test. Adherence did not change significantly in the control group (p = 0.532), whereas the intervention group showed a significant increase in adherence scores (Δ = 7.20; p < 0.001). Post-intervention adherence was significantly higher in the intervention group than in the control group (p < 0.001). These findings indicate that integrating SatuObat into pharmacist-led care can substantially enhance medication adherence among hypertensive patients in community pharmacy settings and support the wider adoption of digital pharmaceutical care in low- and middle-income countries.
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Author Biographies

  • Yugo Susanto, Universitas Airlangga

    Doctoral Program in Pharmaceutical Sciences, Universitas Airlangga, Surabaya, East Java, Indonesia

    Department of Pharmacy, Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin, Banjarmasin, South Kalimantan, Indonesia

  • Andi Hermansyah, Universitas Airlangga

    Department of Pharmacy Practice, Universitas Airlangga, Surabaya, East Java, Indonesia

    Innovative Pharmacy Practice and Integrated Outcomes Research (INACORE), Universitas Airlangga, Surabaya, East Java, Indonesia

  • Muhammad Ashar, Universitas Negeri Malang

    Department of Electrical Engineering and Informatics, Universitas Negeri Malang, Malang, East Java, Indonesia

  • Saybah Humairah, Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

    Department of Pharmacy, Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin, Banjarmasin, South Kalimantan, Indonesia

  • Devi Ristian Octavia, Universitas Muhammadiyah Lamongan

    Department of Pharmacy, Universitas Muhammadiyah Lamongan, Lamongan, East Java, Indonesia

  • Long Chiau Ming, Sunway University

    Faculty of Medical and Life Sciences, Sunway University, Subang Jaya, Selangor Darul Ehsan, Malaysia

  • Muhammad Junaid Farrukh, UCSI University

    Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia

  • Zaheer-Ud-Din Babar, Qatar University

    Department of Clinical Pharmacy and Practice, Qatar University, Doha, Qatar

  • Ronny Faslah, Politeknik Negeri Banjarmasin

    Department of Information Systems, Politeknik Negeri Banjarmasin, Banjarmasin, South Kalimantan, Indonesia

  • Abdul Rahem, Universitas Airlangga

    Department of Pharmacy Practice, Universitas Airlangga, Surabaya, East Java, Indonesia

  • Yuni Priyandani, Universitas Airlangga

    Department of Pharmacy Practice, Universitas Airlangga, Surabaya, East Java, Indonesia

  • Gusti Noorrizka Veronika Achmad, Universitas Airlangga

    Department of Pharmacy Practice, Universitas Airlangga, Surabaya, East Java, Indonesia

References

To be published

Published

09/30/2026

Issue

Section

Clinical-Community Pharmacy

Categories

How to Cite

1.
Susanto Y, Hermansyah A, Ashar M, Humairah S, Octavia DR, Ming LC, et al. Effectiveness of Digital Pharmaceutical Care Intervention on Medication Adherence in Hypertensive Patients: A Quasi-Experimental Study in Banjarmasin, South Kalimantan. Borneo J Pharm [Internet]. 2026 Sept. 30 [cited 2026 Nov. 14];9(3). Available from: https://journal.umpr.ac.id/index.php/bjop/article/view/12742

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