Antioxidant Activity, Total Phenolics, and Total Flavonoids Content of Bajakah Tampala (Spatholobus littoralis): The Indigenous Herbal Medicine from Kalimantan

Authors

DOI:

https://doi.org/10.33084/bjop.v7i3.6609

Keywords:

Total flavonoid content, Spatholobus littoralis, Total phenolic content, antioxidant

Abstract

Bajakah tampala (Spatholobus littoralis), a medicinal plant traditionally used in Indonesia, particularly on Kalimantan Island, has garnered interest for its potential health benefits. However, scientific evidence remains scarce. This study investigated the antioxidant activity of S. littoralis extract and its total phenolic and flavonoid content. Ethanol extraction and evaporation were used to prepare the extract. The DPPH method assessed antioxidant activity, while Folin–Ciocalteu and AlCl3 complexation methods quantified total phenolics and flavonoids, respectively. The S. littoralis extract exhibited strong antioxidant activity with an IC50 value of 54.19 ± 8.15 µg/mL. Additionally, the extract contained substantial levels of phenolics (0.649 ± 0.026% GAE) and flavonoids (1.084 ± 0.043% QE). These findings suggest a link between the high phenolic and flavonoid content of S. littoralis extract and its observed strong antioxidant activity.

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Author Biographies

  • Nurkhasanah Mahfudh, Universitas Ahmad Dahlan

    Department of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Special Region of Yogyakarta, Indonesia

  • Habib Basyanur Murdi, Universitas Ahmad Dahlan

    Department of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Special Region of Yogyakarta, Indonesia

  • Dwi Utami, Universitas Ahmad Dahlan

    Department of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Special Region of Yogyakarta, Indonesia

  • Mustofa Ahda, Universitas Ahmad Dahlan

    Department of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Special Region of Yogyakarta, Indonesia

  • Siti Nashihah, Universitas Muhammadiyah Banjarmasin

    Department of Pharmacy, Universitas Muhammadiyah Banjarmasin, Barito Kuala, South Kalimantan, Indonesia

  • Andika Andika, Universitas Muhammadiyah Banjarmasin

    Department of Pharmacy, Universitas Muhammadiyah Banjarmasin, Barito Kuala, South Kalimantan, Indonesia

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Published

08/30/2024

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Section

Pharmacognosy-Phytochemistry

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How to Cite

1.
Mahfudh N, Murdi HB, Utami D, Ahda M, Nashihah S, Andika A. Antioxidant Activity, Total Phenolics, and Total Flavonoids Content of Bajakah Tampala (Spatholobus littoralis): The Indigenous Herbal Medicine from Kalimantan. Borneo J Pharm [Internet]. 2024 Aug. 30 [cited 2026 Nov. 10];7(3):247-53. Available from: https://journal.umpr.ac.id/index.php/bjop/article/view/6609

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