Original Research Article

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  • Original Research Article

    Identification of Gene Variations Associated with Diabetic Neuropathy Using Bioinformatics Approach

    Siti Fatimah Sultan (1), Adisti Putri Novriyanti (1), Siti Rohmah (1), Lalu Muhammad Irham (2), Nanik Sulistyani (1), Muhammad Ma'ruf (3)
    (1) Universitas Ahmad Dahlan, Indonesia,
    (2) National Research and Innovation Agency, Indonesia,
    (3) Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin, Indonesia
    48-59
    Abstract Views : 509
    Download :289
    10.33084/bjop.v9i1.7148
    Views: 509Downloads: 289
    DOI: https://doi.org/10.33084/bjop.v9i1.7148
  • Original Research Article

    Molecular Docking and QSAR Analysis of N-(Ethylcarbamothioyl)benzamide Derivatives as Dual Estrogen-Alpha and Progesterone Receptors Inhibitor for Breast Cancer

    Anung Kustriyani (1), Bambang Tri Purwanto (1), Tri Widiandani (1), Khoirunnisa Muslimawati (2)
    (1) Universitas Airlangga, Indonesia,
    (2) Universitas Lambung Mangkurat, Indonesia
    77-87
    Abstract Views : 351
    Download :225
    10.33084/bjop.v9i1.10948
    Views: 351Downloads: 225
    DOI: https://doi.org/10.33084/bjop.v9i1.10948
  • Original Research Article

    Computation and Experimental Approaches to Uncover the Antidiabetic Potential of Insulin Leaf (Tithonia diversifolia) Extract Based on Flavonoid Constituents

    Masniah Masniah (1), Eko Suhartono (1), Fujiati Fujiati (1), Muhammad Ali Faisal (1), Budu Budu (2), Mohammad Bakhriansyah (1), Istiana Istiana (1), Dewi Indah Noviana Pratiwi (1)
    (1) Universitas Lambung Mangkurat, Indonesia,
    (2) Universitas Hasanuddin, Indonesia
    13-23
    Abstract Views : 466
    Download :506
    10.33084/bjop.v9i1.11515
    Views: 466Downloads: 506
    DOI: https://doi.org/10.33084/bjop.v9i1.11515
  • Original Research Article

    Molecular Docking and In Silico Evaluation of Beluntas (Pluchea indica) Phytochemicals as Potential Angiotensin-Converting Enzyme Inhibitors for Hypertension Treatment

    Achmad Ramadhanna’il Rasjava (1), Nabila Hadiah Akbar (1), Aulia Rhamdani Arfan (1), Dyah Ayu Pramoda Wardani (1), Aditya Maulana Perdana Putra (1), Khoirunnisa Muslimawati (1), Putri Helena Junjung Buih (1), Taufik Muhammad Fakih (2)
    (1) Universitas Lambung Mangkurat, Indonesia,
    (2) Universitas Islam Bandung, Indonesia
    88-100
    Abstract Views : 533
    Download :280
    10.33084/bjop.v9i1.9706
    Views: 533Downloads: 280
    DOI: https://doi.org/10.33084/bjop.v9i1.9706
  • Original Research Article

    Optimization of Gel Cream Containing HAMIN™ and HPMC K100M as Bases for Topical Delivery of Diclofenac Sodium

    Lina Winarti (1), Amirah Mohd Gazzali (2), Fania Mufti Mufidah (1), Fahrauk Faramayuda (3), Evi Umayah Ulfa (1), Dwi Nurahmanto (1), Muhammad Hilmi Afthoni (1), Liza Pratiwi (4), Bambang Wijianto (4)
    (1) Universitas Jember, Indonesia,
    (2) Universiti Sains Malaysia, Malaysia,
    (3) Universitas Jenderal Achmad Yani, Indonesia,
    (4) Universitas Tanjungpura, Indonesia
    35-47
    Abstract Views : 577
    Download :352
    10.33084/bjop.v9i1.10417
    Views: 577Downloads: 352
    DOI: https://doi.org/10.33084/bjop.v9i1.10417
  • Original Research Article

    Synthesis of 4-Hydroxycinnamic Acid from Malonic Acid and 4-Hydroxybenzaldehyde as Starting Materials with the Variation of the Reflux Time

    Iin Narwanti (1), Fahmi Humaidi Abdillah (1)
    (1) Universitas Ahmad Dahlan, Indonesia
    60-70
    Abstract Views : 437
    Download :220
    10.33084/bjop.v9i1.9356
    Views: 437Downloads: 220
    DOI: https://doi.org/10.33084/bjop.v9i1.9356
  • Original Research Article

    Formulation and The Hen's Egg Chorioallantoic Membrane (HET-CAM) Test to Predict Irritation Potential of FCEE and FCEA Facial Cleansing Gel

    Dina Yuspita Sari (1), Evi Eriani (1), Ibnu Afif (1), Erick Ferdian (1), Ika Ristia Rahman (1)
    (1) Akademi Farmasi Yarsi Pontianak, Indonesia
    24-34
    Abstract Views : 731
    Download :1514
    10.33084/bjop.v9i1.8887
    Views: 731Downloads: 1514
    DOI: https://doi.org/10.33084/bjop.v9i1.8887
  • Original Research Article

    Phytochemical Insights into Rhizophora stylosa: pH-Dependent Extraction, Antioxidant Activity, and Enzyme Inhibition Potential

    Dwi Bagus Pambudi (1), Muhtadi Muhtadi (2), Maryati Maryati (2)
    (1) Universitas Muhammadiyah Pekajangan Pekalongan, Indonesia,
    (2) Universitas Muhammadiyah Surakarta, Indonesia
    1-12
    Abstract Views : 664
    Download :593
    10.33084/bjop.v9i1.11158
    Views: 664Downloads: 593
    DOI: https://doi.org/10.33084/bjop.v9i1.11158
  • Original Research Article

    Evaluation of Antioxidant Potential and Phytochemical Composition of Carrageenan Extracts from Nine Edible Seaweed Species

    Katrin Mae Mendoza Ortega (1), Eric Camilo Rubia Punzalan (1), Ma Carmen Ablan Lagman (1)
    (1) De La Salle University, Philippines
    101-110
    Abstract Views : 405
    Download :206
    10.33084/bjop.v9i1.8294
    Views: 405Downloads: 206
    DOI: https://doi.org/10.33084/bjop.v9i1.8294
  • Original Research Article

    Interventions on Costs and Survival Rates of Lung Cancer Patients

    Fitriana Yuliastuti (1), Nurfina Dian Kartikawati (1), Missya Putri Kurnia Pradani (1), Cut Dewi Bunga (1), Roshan Kumar Mahato (2)
    (1) Universitas Muhammadiyah Magelang, Indonesia,
    (2) Khon Kaen University, Thailand
    398-407
    Abstract Views : 518
    Download :502
    10.33084/bjop.v8i4.10049
    Views: 518Downloads: 502
    DOI: https://doi.org/10.33084/bjop.v8i4.10049
  • Original Research Article

    Antibacterial and Antibiofilm Activity of the Extract and Fractions of Kelakai (Stenochlaena palustris (Burm.F) Bedd) against Methicillin-resistant Staphylococcus aureus

    Joko Priyanto Wibowo (1), Restu Dara Wewengkang (1), Medina Nurrahmah (1), Nurul Fajeriyati (1), Irfan Zamzani (2), Afif Pranaya Jati (3)
    (1) Universitas Muhammadiyah Banjarmasin, Indonesia,
    (2) Institut Teknologi Bandung, Indonesia,
    (3) Monash University, Australia
    379-387
    Abstract Views : 785
    Download :639
    10.33084/bjop.v8i4.8991
    Views: 785Downloads: 639
    DOI: https://doi.org/10.33084/bjop.v8i4.8991
  • Original Research Article

    Pogostemon cablin from North Konawe Targets MCF-7 Cells and Inflammatory Responses Through Protein Denaturation and Membrane Stabilization

    Adryan Fristiohady (1), Jafriati Jafriati (1), Irvan Anwar (1), Rathapon Asasutjarit (2), La Ode Muhammad Julian Purnama (2), Lidya Agriningsih Haruna (2), Agung Wibawa Mahatva Yodha (3), Hariana Hariana (1), Mentarry Bafadal (4)
    (1) Universitas Halu Oleo, Indonesia,
    (2) Thammasat University, Thailand,
    (3) Politeknik Bina Husada Kendari, Indonesia,
    (4) Universitas Mulawarman, Indonesia
    326-334
    Abstract Views : 749
    Download :605
    10.33084/bjop.v8i4.10168
    Views: 749Downloads: 605
    DOI: https://doi.org/10.33084/bjop.v8i4.10168
  • Original Research Article

    Granulation Methods Dependent Physical Characteristics of Chitosan Effervescent Granule Suspension from Mangrove Crab (Scylla serrata) Shell

    Hilya Nur Imtihani (1), Nimas Ajeng Isbandyah (2), Endah Susanti (2), Andhika Dwi Aristyawan (2)
    (1) Universitas Hang Tuah, Indonesia,
    (2) Akademi Farmasi Surabaya, Indonesia
    344-352
    Abstract Views : 425
    Download :514
    10.33084/bjop.v8i4.7334
    Views: 425Downloads: 514
    DOI: https://doi.org/10.33084/bjop.v8i4.7334
  • Original Research Article

    Phenolic, Flavonoid, and Antioxidant Profiles of Sago (Metroxylon sagu Rottb.) Leaf Ethanol Extract

    Muhammad Isrul (1), Bai Athur Ridwan (1), Ahmad Syaiful (1), Azlimin Azlimin (1), Tenri Zulfa Ayu Dwi Putri (1), Eviyanti Jambilu (1), Mahfuzun Bone (2), Vina Maulidya (2)
    (1) Universitas Mandala Waluya, Indonesia,
    (2) Universitas Mulawarman, Indonesia
    335-343
    Abstract Views : 698
    Download :642
    10.33084/bjop.v8i4.7818
    Views: 698Downloads: 642
    DOI: https://doi.org/10.33084/bjop.v8i4.7818
  • Original Research Article

    Protective Effect of Amorphophallus oncophyllus against Indomethacin-Induced Duodenal Mucosal Injury in Rats via Inhibition of Inflammatory Cell Infiltration

    Yuani Setiawati (1), Rochmah Kurnijasanti (1), Annette D'Arqom (1), Jusak Nugraha (1), Oski Illiandri (2), Sri Agus Sudjarwo (1)
    (1) Airlangga University, Indonesia,
    (2) Lambung Mangkurat University, Indonesia
    388-397
    Abstract Views : 436
    Download :363
    10.33084/bjop.v8i4.10233
    Views: 436Downloads: 363
    DOI: https://doi.org/10.33084/bjop.v8i4.10233
  • Original Research Article

    Kelor (Moringa oleifera) Bioactive Compounds as Potential Anti-Breast Cancer Agents: In Silico Studies

    Saeful Amin (1), Vanessa Angelica Sheryl (1), Ade Yeni Aprillia (1), Anisa Pebiansyah (1)
    (1) Universitas Bakti Tunas Husada, Indonesia
    353-367
    Abstract Views : 551
    Download :562
    10.33084/bjop.v8i4.7435
    Views: 551Downloads: 562
    DOI: https://doi.org/10.33084/bjop.v8i4.7435
  • Original Research Article

    Antibacterial Activity and Bioautography Test of Ethanol Extract of Kitolod (Isotoma longiflora (L.) C. Presl.) Leaves against Staphylococcus aureus and Salmonella typhi using Ultrasound-Assisted Extraction

    Fajrin Ahidannisa Yuhdi (1), Ika Trisharyanti Dian Kusumowati (1)
    (1) Universitas Muhammadiyah Surakarta, Indonesia
    368-378
    Abstract Views : 1116
    Download :578
    10.33084/bjop.v8i4.6699
    Views: 1116Downloads: 578
    DOI: https://doi.org/10.33084/bjop.v8i4.6699
  • Original Research Article

    In Silico Analysis of the Antigastritis Activity of Gedi (Abelmoschus manihot) Flower Flavonoids on H2 Receptor

    Gregorius Giani Adikila (1), Yuanita Amalia Hariyanto (1), Trina Ekawati Tallei (1), Elly Juliana Suoth (1), Sri Sudewi (1), Fatimawali Fatimawali (1)
    (1) Sam Ratulangi University, Indonesia
    228-241
    Abstract Views : 596
    Download :637
    10.33084/bjop.v8i3.7586
    Views: 596Downloads: 637
    DOI: https://doi.org/10.33084/bjop.v8i3.7586
  • Original Research Article

    Comparison of Characteristics and Antibacterial Activity of Mandai Cempedak Vinegar with Variations in Fermentation Methods

    Indah Woro Utami (1), Sapri Sapri (1), Nishia Waya Meray (1), Rezia Elok Canrika (1)
    (1) Universitas Mulia, Indonesia
    263-271
    Abstract Views : 776
    Download :703
    10.33084/bjop.v8i3.9140
    Views: 776Downloads: 703
    DOI: https://doi.org/10.33084/bjop.v8i3.9140
  • Original Research Article

    Molecular Docking Analysis of Flavonoids from Syzygium cumini (L.) Skeels: Proapoptotic Potential as an Anticancer Mechanism

    Nur Sofiatul Aini (1), Arif Nur Muhammad Ansori (2), Muhammad Hermawan Widyananda (3), Viol Dhea Kharisma (1), Ahmad Affan Ali Murtadlo (1), Mochammad Aqilah Herdiansyah (1), Maksim Rebezov (4), Pavel Burkov (5), Petr Gudz (6), Marina Derkho (5), Tatyana Bezhinar (5), Nikolai Maksimiuk (6), Munawir Sazali (7), Hery Purnobasuki (1), Rollando Rollando (8), Aswin Rafif Khairullah (9), Teguh Hari Sucipto (1)
    (1) Universitas Airlangga, Indonesia,
    (2) Uttaranchal University, India,
    (3) Universitas Brawijaya, Indonesia,
    (4) Ural State Agrarian University, Russian Federation,
    (5) South Ural State Agrarian University, Russian Federation,
    (6) Yaroslav-the-Wise Novgorod State University, Russian Federation,
    (7) Universitas Islam Negeri Mataram, Indonesia,
    (8) Universitas Ma Chung, Indonesia,
    (9) National Research and Innovation Agency of the Republic of Indonesia, Indonesia
    252-262
    Abstract Views : 1411
    Download :728
    10.33084/bjop.v8i3.9843
    Views: 1411Downloads: 728
    DOI: https://doi.org/10.33084/bjop.v8i3.9843
  • Original Research Article

    Effect of Javanese Chili (Piper retrofractum) and Lemon (Citrus limon) Formula on Total Cholesterol Levels in Male White Rats

    Lusi Agus Setiani (1), Nina Herlina (1), Friska Noerfitria Ramadhani (1)
    (1) Pakuan University, Indonesia
    210-218
    Abstract Views : 713
    Download :673
    10.33084/bjop.v8i3.8688
    Views: 713Downloads: 673
    DOI: https://doi.org/10.33084/bjop.v8i3.8688
  • Original Research Article

    Physicochemical Profile and Stability of Red Ginger (Zingiber officinale var. rubrum) SNEDDS as Potential Aphrodisiac

    Edo Pratama (1), M. Ainun Najib Aly (1), Farida Istiqamah (2), Retno Widyowati (1), Sukardiman Sukardiman (1)
    (1) Airlangga University, Indonesia,
    (2) Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin, Indonesia
    282-291
    Abstract Views : 717
    Download :644
    10.33084/bjop.v8i3.9691
    Views: 717Downloads: 644
    DOI: https://doi.org/10.33084/bjop.v8i3.9691
  • Original Research Article

    Comparison of Chromatogram Profiles of Red Ginger (Zingiber officinale var. rubrum Theilade) Rhizome Essential Oil Based on Differences in Growing Places

    Anita Agustina Styawan (1), Helmi Mustofa (1), Awal Prichatin Kusumadewi (2)
    (1) Universitas Muhammadiyah Klaten, Indonesia,
    (2) Rumah Sakit Umum Pusat Dr. Sardjito, Indonesia
    272-281
    Abstract Views : 1758
    Download :533
    10.33084/bjop.v8i3.9311
    Views: 1758Downloads: 533
    DOI: https://doi.org/10.33084/bjop.v8i3.9311
  • Original Research Article

    Balancing Need and Feasibility: Stakeholder Insights on Frequent Blood Glucose Monitoring in Indonesia

    Agnes Christie Rinda (1), Umi Athiyah (2), Andi Hermansyah (2)
    (1) Universitas Sari Mulia, Indonesia,
    (2) Universitas Airlangga, Indonesia
    292-304
    Abstract Views : 557
    Download :584
    10.33084/bjop.v8i3.9848
    Views: 557Downloads: 584
    DOI: https://doi.org/10.33084/bjop.v8i3.9848
  • Original Research Article

    Molecular Docking Study of Substituted Benzamide Derivatives as Analgesic Candidates

    Rahmawati Rahmawati (1), Rais Razak (1), Muammar Fawwaz (1)
    (1) Indonesian Muslim University of Makassar, Indonesia
    242-251
    Abstract Views : 593
    Download :607
    10.33084/bjop.v8i3.8715
    Views: 593Downloads: 607
    DOI: https://doi.org/10.33084/bjop.v8i3.8715