Original Research Article

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  • Original Research Article

    2D-QSAR, Docking, Molecular Dynamics Simulations with the MM/GBSA Approaches against Graves' Disease and PTPN22

    Emmanuel Israel Edache (1), Adamu Uzairu (2), Paul Andrew Mamza (3), Gideon Adamu Shallangwa (4)
    (1) University of Maiduguri , Nigeria ,
    (2) Ahmadu Bello University , Nigeria ,
    (3) Ahmadu Bello University , Nigeria ,
    (4) Ahmadu Bello University , Nigeria ,
    229-248
    Abstract Views : 854
    Download :555
    10.33084/bjop.v6i3.4915
    DOI: https://doi.org/10.33084/bjop.v6i3.4915
  • Original Research Article

    Fibrinolytic Protease Activity of Crude Enzyme from Fermented Sunflower (Helianthus annuus) and Common Bean (Phaseolus vulgaris) seeds by Rhizopus microsporus var. oligosporus FNCC 6010 in Solid State Fermentation

    Rebhika Lusiana (1), Achmad Toto Poernomo (2), Achmad Syahrani (3)
    (1) Universitas Airlangga , Indonesia ,
    (2) Universitas Airlangga , Indonesia ,
    (3) Universitas Airlangga , Indonesia ,
    295-304
    Abstract Views : 646
    Download :836
    10.33084/bjop.v6i3.4665
    DOI: https://doi.org/10.33084/bjop.v6i3.4665
  • Original Research Article

    Antibacterial Effect of Cinnamon and Citronella Oils Combination Against Acne-Related Bacteria

    Sri Mulyaningsih (1), Arya Guna Ramadhan (2), Widyasari Putranti (3)
    (1) Universitas Ahmad Dahlan , Indonesia ,
    (2) Universitas Ahmad Dahlan , Indonesia ,
    (3) Universitas Ahmad Dahlan , Indonesia ,
    305-313
    Abstract Views : 1079
    Download :743
    10.33084/bjop.v6i3.4735
    DOI: https://doi.org/10.33084/bjop.v6i3.4735
  • Original Research Article

    Potential Antidiabetic Compounds from Anogeissus leiocarpus: Molecular Docking, Molecular Dynamic Simulation, and ADMET Studies

    Mubarak Muhammad Dahiru (1), Neksumi Musa (2), AbdulAzeez Mumsiri Abaka (3), Maimuna Abdulrahman Abubakar (4)
    (1) Adamawa State Polytechnic , Nigeria ,
    (2) Adamawa State Polytechnic , Nigeria ,
    (3) Adamawa State Polytechnic , Nigeria ,
    (4) Modibbo Adama University , Nigeria ,
    249-277
    Abstract Views : 1036
    Download :768
    10.33084/bjop.v6i3.5027
    DOI: https://doi.org/10.33084/bjop.v6i3.5027
  • Original Research Article

    Public Perspective on Hyperlipidemia Drugs and Sentiments About Hyperlipidemia on Twitter

    Murojil Hasan (1), Chairun Wiedyaningsih (2), Nanang Munif Yasin (3)
    (1) Universitas Gadjah Mada , Indonesia ,
    (2) Universitas Gadjah Mada , Indonesia ,
    (3) Universitas Gadjah Mada , Indonesia ,
    330-338
    Abstract Views : 821
    Download :501
    10.33084/bjop.v6i3.4936
    DOI: https://doi.org/10.33084/bjop.v6i3.4936
  • Original Research Article

    Characterization of Secondary Metabolites Profile from Methanol Fraction of Temurui (Murraya koenigii (Linn.) Spreng) Leaves Using UPLC-MS

    Intania Permata (1), Adlis Santoni (2), Afrizal Afrizal (3), Trisno Afandi (4)
    (1) Politeknik ATI Padang , Indonesia ,
    (2) Universitas Andalas , Indonesia ,
    (3) Universitas Andalas , Indonesia ,
    (4) Politeknik Teknologi Kimia Industri Medan , Indonesia ,
    278-286
    Abstract Views : 748
    Download :624
    10.33084/bjop.v6i3.4662
    DOI: https://doi.org/10.33084/bjop.v6i3.4662
  • Original Research Article

    Aloe vera Gel Ameliorates Fat-Rich and High Fructose (FRHF) Diet-Induced Pancreatic and Splenic Damage in Mice

    Nathan Isaac Dibal (1), Zainab Muhammad Goni (2), Martha Orendu Oche Attah (3), Umar Imam (4), Muhammad Abdullahi (5), Muzammil Bashir (6), Usman Adam (7), Fatima Aisami (8), Mohammed Shuwa (9), Sunday Joseph Manye (10), Madu Nom Gadzama (11), Musa Samaila Chiroma (12), Helga Bedan Ishaya (13)
    (1) University of Maiduguri , Nigeria ,
    (2) University of Maiduguri , Nigeria ,
    (3) Cyprus International University , Cyprus ,
    (4) University of Maiduguri , Nigeria ,
    (5) University of Maiduguri , Nigeria ,
    (6) University of Maiduguri , Nigeria ,
    (7) University of Maiduguri , Nigeria ,
    (8) University of Maiduguri , Nigeria ,
    (9) University of Maiduguri , Nigeria ,
    (10) University of Maiduguri , Nigeria ,
    (11) University of Maiduguri , Nigeria ,
    (12) Newcastle University Medicine Malaysia , Malaysia ,
    (13) University of Maiduguri , Nigeria ,
    222-228
    Abstract Views : 654
    Download :610
    10.33084/bjop.v6i3.5351
    DOI: https://doi.org/10.33084/bjop.v6i3.5351
  • Original Research Article

    Phytochemical Analysis and Anti-Inflammatory Activity of The Combination of Trigona apicalis propolis Extract and Honey

    Paula Mariana Kustiawan (1), Chaerul Fadly Mochtar Luthfi M (2), Sinta Ratna Dewi (3), Jati Pratiwi (4), Novia Misnawati Aisyiyah (5), Alfin Syahrian Dwi Nugraha (6), Irfan Muris Setiawan (7)
    (1) Universitas Muhammadiyah Kalimantan Timur , Indonesia ,
    (2) Universitas Muhammadiyah Kalimantan Timur , Indonesia ,
    (3) Universitas Muhammadiyah Kalimantan Timur , Indonesia ,
    (4) Universitas Muhammadiyah Kalimantan Timur , Indonesia ,
    (5) Universitas Muhammadiyah Kalimantan Timur , Indonesia ,
    (6) Universitas Muhammadiyah Kalimantan Timur , Indonesia ,
    (7) Universitas Gadjah Mada , Indonesia ,
    125-132
    Abstract Views : 937
    Download :744
    10.33084/bjop.v6i2.4696
    DOI: https://doi.org/10.33084/bjop.v6i2.4696
  • Original Research Article

    Ointment Formulation of Tapak Dara (Catharanthus roseus (L.) G. Don) Flower Ethanol Extract and its Activity in Burn-Healing

    Leny Leny (1), Tetty Noverita Khairani Situmorang (2), Rensus Siagian (3), Ihsanul Hafiz (4), Benni Iskandar (5)
    (1) Institut Kesehatan Helvetia , Indonesia ,
    (2) Institut Kesehatan Helvetia , Indonesia ,
    (3) Institut Kesehatan Helvetia , Indonesia ,
    (4) Institut Kesehatan Helvetia , Indonesia ,
    (5) Taipei Medical University , Taiwan, Province of China ,
    182-189
    Abstract Views : 1113
    Download :1280
    10.33084/bjop.v6i2.3155
    DOI: https://doi.org/10.33084/bjop.v6i2.3155
  • Original Research Article

    Identification of Biological Risk Genes and Candidate Drugs for Psoriasis Vulgaris by Utilizing the Genomic Information

    Lisza Niarisessa (1), Anisa Nova Puspitaningrum (2), Arief Rahman Afief (3), Dyah Aryani Perwitasari (4), Wirawan Adikusuma (5), Rocky Cheung (6), Abdi Wira Septama (7), Lalu Muhammad Irham (8)
    (1) Universitas Ahmad Dahlan , Indonesia ,
    (2) Universitas Ahmad Dahlan , Indonesia ,
    (3) Universitas Ahmad Dahlan , Indonesia ,
    (4) Universitas Ahmad Dahlan , Indonesia ,
    (5) Universitas Muhammadiyah Mataram , Indonesia ,
    (6) University of California, Los Angeles , United States ,
    (7) National Research and Innovation Agency Republic of Indonesia , Indonesia ,
    (8) Universitas Ahmad Dahlan , Indonesia ,
    110-119
    Abstract Views : 987
    Download :775
    10.33084/bjop.v6i2.4217
    DOI: https://doi.org/10.33084/bjop.v6i2.4217
  • Original Research Article

    Analysis of Management Elements in Antibiotic Inventory Control with EOQ and MMSL Methods at Aisyiyah Bojonegoro Hospital

    Pramono Apriawan Wijayanto (1), Ayun Sriatmi (2), Sutopo Patria Jati (3)
    (1) Universitas Diponegoro , Indonesia ,
    (2) Universitas Diponegoro , Indonesia ,
    (3) Universitas Diponegoro , Indonesia ,
    208-221
    Abstract Views : 705
    Download :551
    10.33084/bjop.v6i2.3494
    DOI: https://doi.org/10.33084/bjop.v6i2.3494
  • Original Research Article

    Antioxidant Activity and Phytochemicals of Locally Consumed Plant Foods from Baguio City, Philippines

    Paolo Robert P. Bueno (1), Rachel Camille R. Cabrera (2), Gracia Fe B. Yu (3)
    (1) University of the Philippines Manila , Philippines ,
    (2) University of the Philippines Manila , Philippines ,
    (3) University of the Philippines Manila , Philippines ,
    190-207
    Abstract Views : 2527
    Download :1042
    10.33084/bjop.v6i2.4546
    DOI: https://doi.org/10.33084/bjop.v6i2.4546
  • Original Research Article

    Tentative Identification of Compounds, Antioxidant, and Antimicrobial Activity of the Edible Part of Benincasa hispida L. fruit (Cucurbitaceae)

    Carla Wulandari Sabandar (1), Harni Sartika Kamaruddin (2), Reskiya Nur Insani (3), Rana Triana Amin (4), Zulkifli Zulkifli (5), Tien Tien (6)
    (1) Universitas Sembilanbelas November Kolaka , Indonesia ,
    (2) Universitas Sembilanbelas November Kolaka , Indonesia ,
    (3) Universitas Sembilanbelas November Kolaka , Indonesia ,
    (4) Universitas Sembilanbelas November Kolaka , Indonesia ,
    (5) Universitas Sembilanbelas November Kolaka , Indonesia ,
    (6) Universitas Halu Oleo , Indonesia ,
    133-146
    Abstract Views : 1039
    Download :685
    10.33084/bjop.v6i2.4350
    DOI: https://doi.org/10.33084/bjop.v6i2.4350
  • Original Research Article

    In-Silico Design and Evaluation of the Anti-Wolbachia Potential of Boron-Pleuromutilins

    Fabian Audu Ugbe (1), Gideon Adamu Shallangwa (2), Adamu Uzairu (3), Ibrahim Abdulkadir (4)
    (1) Ahmadu Bello University , Nigeria ,
    (2) Ahmadu Bello University , Nigeria ,
    (3) Ahmadu Bello University , Nigeria ,
    (4) Ahmadu Bello University , Nigeria ,
    168-181
    Abstract Views : 537
    Download :396
    10.33084/bjop.v6i2.4677
    DOI: https://doi.org/10.33084/bjop.v6i2.4677
  • Original Research Article

    Solubility and Scale-Up Potency of Norfloxacin-Urea Co-Crystal Prepared by Ultrasound-Assisted Slurry Co-Crystallization Method

    Fikri Alatas (1), Dery Stiawan (2), Nur Achsan Al-Hakim (3)
    (1) Universitas Jenderal Achmad Yani , Indonesia ,
    (2) Universitas Jenderal Achmad Yani , Indonesia ,
    (3) Universitas Jenderal Achmad Yani , Indonesia ,
    158-167
    Abstract Views : 681
    Download :604
    10.33084/bjop.v6i2.4173
    DOI: https://doi.org/10.33084/bjop.v6i2.4173
  • Original Research Article

    Antioxidant Activity of n-hexane and Etil Acetate Fractions of Bangkal (Nauclea subdita (Korth.) Steud.) Leaves

    Arnida Arnida (1), Al Madani (2), Sutomo Sutomo (3)
    (1) Universitas Lambung Mangkurat , Indonesia ,
    (2) Universitas Lambung Mangkurat , Indonesia ,
    (3) Universitas Lambung Mangkurat , Indonesia ,
    147-157
    Abstract Views : 920
    Download :690
    10.33084/bjop.v6i2.4738
    DOI: https://doi.org/10.33084/bjop.v6i2.4738
  • Original Research Article

    Changes in Mean Arterial and Blood Pressure in Using Nicardipine in Hypertensive Crisis Patients at the Hajj General Hospital Surabaya from August to December 2021

    Selly Septi Fandinata (1), Rizky Darmawan (2), Ninik Mas Ulfa (3), Deddy Aryanda Putra (4)
    (1) Akademi Farmasi Surabaya , Indonesia ,
    (2) Akademi Farmasi Surabaya , Indonesia ,
    (3) Akademi Farmasi Surabaya , Indonesia ,
    (4) Universitas Airlangga , Indonesia ,
    79-86
    Abstract Views : 820
    Download :913
    10.33084/bjop.v6i1.3493
    DOI: https://doi.org/10.33084/bjop.v6i1.3493
  • Original Research Article

    Chemical Screening and Antioxidant Activity of Ethyl Acetate Fraction and Residue from Lansium domesticum Ethanolic Extract

    Pratiwi Apridamayanti (1), Rafika Sari (2)
    (1) Universitas Tanjungpura , Indonesia ,
    (2) Universitas Tanjungpura , Indonesia ,
    31-40
    Abstract Views : 1102
    Download :803
    10.33084/bjop.v6i1.3867
    DOI: https://doi.org/10.33084/bjop.v6i1.3867
  • Original Research Article

    Acute Toxicity of Self-Nanoemulsifying Drug Delivery System of Ipomoea reptans Poir Leaves Extract on Female Wistar Rats

    Cynthia Astiti Putri (1), Farida Hayati (2), Lutfi Chabib (3), Muhammad Iqbal Pangestu (4)
    (1) Universitas Islam Indonesia , Indonesia ,
    (2) Universitas Islam Indonesia , Indonesia ,
    (3) Universitas Islam Indonesia , Indonesia ,
    (4) Universitas Islam Indonesia , Indonesia ,
    1-7
    Abstract Views : 577
    Download :619
    10.33084/bjop.v6i1.2099
    DOI: https://doi.org/10.33084/bjop.v6i1.2099
  • Original Research Article

    Molecular Docking Investigation, Pharmacokinetic Analysis, and Molecular Dynamic Simulation of Some Benzoxaborole-Benzimidazole Hybrids: An Approach to Identifying Superior Onchocerca Inhibitors

    Fabian Audu Ugbe (1), Gideon Adamu Shallangwa (2), Adamu Uzairu (3), Ibrahim Abdulkadir (4)
    (1) Ahmadu Bello University , Nigeria ,
    (2) Ahmadu Bello University , Nigeria ,
    (3) Ahmadu Bello University , Nigeria ,
    (4) Ahmadu Bello University , Nigeria ,
    58-78
    Abstract Views : 1042
    Download :1662
    10.33084/bjop.v6i1.3876
    DOI: https://doi.org/10.33084/bjop.v6i1.3876
  • Original Research Article

    Association between Drug-Related Problems and Blood Pressure of Hypertensive Patients Admitted to Universitas Sumatera Utara Hospital

    Mutiara Siahaan (1), Azizah Nasution (2), Wiryanto Wiryanto (3), Iksen Iksen (4)
    (1) Universitas Sumatera Utara , Indonesia ,
    (2) Universitas Sumatera Utara , Indonesia ,
    (3) Universitas Sumatera Utara , Indonesia ,
    (4) Sekolah Tinggi Ilmu Kesehatan Senior Medan , Indonesia ,
    87-92
    Abstract Views : 862
    Download :722
    10.33084/bjop.v6i1.3664
    DOI: https://doi.org/10.33084/bjop.v6i1.3664
  • Original Research Article

    Column Chromatography Fractionation and Antioxidant Activity of Passiflora foetida Leaves

    Nita Triadisti (1), Irfan Zamzani (2)
    (1) Universitas Muhammadiyah Banjarmasin , Indonesia ,
    (2) Universitas Muhammadiyah Banjarmasin , Indonesia ,
    22-30
    Abstract Views : 3224
    Download :1842
    10.33084/bjop.v6i1.1830
    DOI: https://doi.org/10.33084/bjop.v6i1.1830
  • Original Research Article

    Cytotoxic Activity of Ethyl Acetate Extract from Voacanga foetida (Bl.) Rolfe Leaves Against T47D Breast Cancer Cells

    Adriani Susanty (1), Mira Febrina (2), Dian Sanita Putri (3), Ihsan Ikhtiarudin (4), Fatma Sri Wahyuni (5), Dachriyanus Dachriyanus (6)
    (1) Sekolah Tinggi Ilmu Farmasi Riau , Indonesia ,
    (2) Sekolah Tinggi Ilmu Farmasi Riau , Indonesia ,
    (3) Sekolah Tinggi Ilmu Farmasi Riau , Indonesia ,
    (4) Sekolah Tinggi Ilmu Farmasi Riau , Indonesia ,
    (5) Universitas Andalas , Indonesia ,
    (6) Universitas Andalas , Indonesia ,
    8-14
    Abstract Views : 805
    Download :819
    10.33084/bjop.v6i1.3499
    DOI: https://doi.org/10.33084/bjop.v6i1.3499
  • Original Research Article

    Hand Sanitizer Gel Formulation with Laccase Enzyme as an Antibacterial Against Staphylococcus aureus and Escherichia coli

    Sita Heris Anita (1), Asishe Asishe (2), Vilya Syafriana (3), Amelia Febriani (4), Deni Zulfiana (5), Maulida Oktaviani (6), Oktan Dwi Nurhayat (7), Dede Heri Yuli Yanto (8)
    (1) National Research and Innovation Agency Republic of Indonesia , Indonesia ,
    (2) Institut Sains dan Teknologi Nasional , Indonesia ,
    (3) Institut Sains dan Teknologi Nasional , Indonesia ,
    (4) Institut Sains dan Teknologi Nasional , Indonesia ,
    (5) National Research and Innovation Agency Republic of Indonesia , Indonesia ,
    (6) National Research and Innovation Agency Republic of Indonesia , Indonesia ,
    (7) National Research and Innovation Agency Republic of Indonesia , Indonesia ,
    (8) National Research and Innovation Agency Republic of Indonesia , Indonesia ,
    375-383
    Abstract Views : 981
    Download :1189
    10.33084/bjop.v5i4.3683
    DOI: https://doi.org/10.33084/bjop.v5i4.3683
  • Original Research Article

    Phytochemical Composition and Antioxidant Potential of Hyphaene thebaica Fruit

    Muhammad Mubarak Dahiru (1), Margret Samuel Nadro (2)
    (1) Adamawa State Polytechnic , Nigeria ,
    (2) Modibbo Adama University of Technology, Yola , Nigeria ,
    325-333
    Abstract Views : 1279
    Download :1414
    10.33084/bjop.v5i4.3632
    DOI: https://doi.org/10.33084/bjop.v5i4.3632